Protein Alignment PLPP1 and wun2

DIOPT Version :10

• Sequence 1: NP_795714.1
• Gene: PLPP1 / 8611
• HGNCID: 9228
• Length: 285
• Species: Homo sapiens
• Sequence 2: NP_524991.1
• Gene: wun2 / 53558
• FlyBaseID: FBgn0041087
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 253
• Identity: 99/253 - (39%)
• Similarity: 139/253 - (54%)
• Gaps: 26/253 - (10%)

Human    15 LCVL-LASMPMAVLKL-GQIYPFQRGFFCKDNSINYPYHDSTVTSTVLILVGVGLPISSIILGET 77
            ||:| ...:||....| |:  ..:|||||.|:|:.:||.|||:.|.:|.|:...||::.:::.|.
  Fly    95 LCLLSCVGLPMLGFSLWGE--AVKRGFFCDDSSLRHPYRDSTMPSWILYLMCGALPLTVMLVVEF 157

Human    78 L-------------SVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRP 129
            .             |..|:..|........::...|..:|.|:||....|..|:|||||||||||
  Fly   158 FRGQDKRLHSPFPKSTMCSGYHLCHLELPTWLVECYHRMGIFIFGLGVEQLSTNIAKYSIGRLRP 222

Human   130 HFLDVCDPDWSK-INCSD-----GYIEYYICRG---NAERVKEGRLSFYSGHSSFSMYCMLFVAL 185
            ||..:|.|.... ..|||     .|||.:.|..   .::::|:.||||.|||:||:.|.||::.:
  Fly   223 HFYTLCQPVMKDGTTCSDPINAARYIEEFTCAAVDITSKQLKDMRLSFPSGHASFACYSMLYLVI 287

Human   186 YLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILV 243
            ||..||:....|:|...|||.|:..:.|..|:|||||||||||||.|...|...|::|
  Fly   288 YLHRRMQWKQLRMLCHLLQFLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYAVVV 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLPP1	NP_795714.1	PAP2_wunen	99..244	CDD:239479	71/154 (46%)
wun2	NP_524991.1	PAP2_wunen	191..346	CDD:239479	71/155 (46%)