Protein Alignment PLPP1 and CG11425

DIOPT Version :10

• Sequence 1: NP_795714.1
• Gene: PLPP1 / 8611
• HGNCID: 9228
• Length: 285
• Species: Homo sapiens
• Sequence 2: NP_649395.1
• Gene: CG11425 / 40472
• FlyBaseID: FBgn0037167
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 98/262 - (37%)
• Similarity: 148/262 - (56%)
• Gaps: 30/262 - (11%)

Human     2 FDKTRLPYVALDVLCVLLASMPMAVLKLGQIY--PFQRGFFCKDNSINYPYHDSTVTSTVLILVG 64
            |:.:..|.:.|.|..|||..:.:.|....:::  |.:|||||.|.|:.||||::||:.|:|..:|
  Fly     3 FNLSLRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRGFFCDDESLMYPYHENTVSPTLLHWLG 67

Human    65 VGLPISSIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRP 129
            :.||:.|:::.|:.     |.|.........:..:|..:..||:|..::..|..|.|.::|||||
  Fly    68 LYLPLISLVVLESF-----LSHRKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRP 127

Human   130 HFLDVCD---PDWSKINCSD----GYIEY---YICRGN-----AERVKEGRLSFYSGHSSFSMYC 179
            ||..||.   ||.|  :|.|    |.::|   |.||.|     .|.:::..:||.||||:.:.|.
  Fly   128 HFFAVCSPHFPDGS--SCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYG 190

Human   180 MLFVALYLQAR---MKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAI 241
            ::||||:|:.|   ::|.   ||.|.||...||::.:|.:|||.|||||||||..|.:.||..|:
  Fly   191 LVFVALHLRRRRWPLRGS---LLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSAL 252

Human   242 LV 243
            .|
  Fly   253 AV 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLPP1	NP_795714.1	PAP2_wunen	99..244	CDD:239479	67/163 (41%)
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	67/164 (41%)