Protein Alignment PLPP1 and wun

DIOPT Version :10

• Sequence 1: NP_795714.1
• Gene: PLPP1 / 8611
• HGNCID: 9228
• Length: 285
• Species: Homo sapiens
• Sequence 2: NP_724787.1
• Gene: wun / 35966
• FlyBaseID: FBgn0016078
• Length: 379
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 122/272 - (44%)
• Similarity: 166/272 - (61%)
• Gaps: 23/272 - (8%)

Human     3 DKTRLPYVALDVLCVLLASMPMAV-LKLGQIYPFQRGFFCKDNSINYPYHDSTVTSTVLILVGVG 66
            :|..|..|.||||.:|.|..|:.: ..||:  |::|||||.|.|:.:|:|||||.:.:|..:|..
  Fly    83 NKRILCRVGLDVLILLCAGFPILLFFLLGE--PYKRGFFCDDESLKHPFHDSTVRNWMLYFIGAV 145

Human    67 LPISSIILGETLSVYCNLLHSNS------FIRNNY-----IATIYKAIGTFLFGAAASQSLTDIA 120
            :|:..|.:.|.:.........|.      ::..||     :...||.||.:.|||..||..||||
  Fly   146 IPVGVIFIVEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIA 210

Human   121 KYSIGRLRPHFLDVCDPDWSK-INCSDG-----YIEYYICRG---NAERVKEGRLSFYSGHSSFS 176
            |||||||||||:.||.|..:. ..|.|.     ||:.:.|:|   :|..:||.||||.||||||:
  Fly   211 KYSIGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHSSFT 275

Human   177 MYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAI 241
            .:.|:::||||||||....::|||..|||..:.|:.|..|||||||||||||||.|.:.|::.|:
  Fly   276 FFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISAL 340

Human   242 LVAVYVSDFFKE 253
            :||.||||.|::
  Fly   341 VVANYVSDLFQK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLPP1	NP_795714.1	PAP2_wunen	99..244	CDD:239479	81/153 (53%)
wun	NP_724787.1	PAP2_wunen	188..343	CDD:239479	81/154 (53%)