Protein Alignment ACTL6A and Bap55

DIOPT Version :10

• Sequence 1: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_611209.1
• Gene: Bap55 / 36956
• FlyBaseID: FBgn0025716
• Length: 425
• Species: Drosophila melanogaster
• Alignment Length: 442
• Identity: 241/442 - (54%)
• Similarity: 316/442 - (71%)
• Gaps: 30/442 - (6%)

Human     1 MSGG--VYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGM----------VVERDDGSTL 53
            ||||  :|||||:||||||.|.:::|.|||.||.||.:.|:.:|:          ..:.|:.:|.
  Fly     1 MSGGTMLYGGDEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATP 65

Human    54 MEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLH 118
            ...|..|       :|:|||.:.|||.|||..:.:|:||:::||.|:.::|:.|...::||...|
  Fly    66 NNADQRK-------FYVDTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYH 123

Human   119 PVLMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVH 183
            |||.|||.||.|..||||||||||.||:|||||.|.|||.||::||:|.|::|||||||:|:|||
  Fly   124 PVLFSEASWNVRNNREKLTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVH 188

Human   184 DGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQ-VT 247
            :||||.|.:|||||.|||::.|||:..::..|:|.|.|.||||:.|:|.....:..: |||: :|
  Fly   189 EGYVLSQAVVKSPLGGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLR-KLPENLT 252

Human   248 RSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPS 312
            :||.|||...::||||.:||||.::.:||:||||:|||||||||||:.|||:||.||.|.|||
  Fly   253 QSWQNYMLQLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFD-- 315

Human   313 NVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMR 377
                   |.|||...:.:|||||||.|:|..|:|||:|.|||||:|.|.:||||:|..:.|.:.|
  Fly   316 -------NAMLGAGQLASTSVGMCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTR 373

Human   378 LKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP 429
            ||:|:.|.:|||||.:|||||||||:|||||||||.|||||.||..||||||
  Fly   374 LKMISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYEEAGKSQVERKCP 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTL6A	NP_004292.1	ASKHA_NBD_Arp4_ACTL6-like	8..420	CDD:466846	227/422 (54%)
Bap55	NP_611209.1	ASKHA_NBD_Arp4_ACTL6-like	10..416	CDD:466846	227/422 (54%)