Protein Alignment ACTL6A and Arp6

DIOPT Version :10

• Sequence 1: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 94/437 - (21%)
• Similarity: 187/437 - (42%)
• Gaps: 67/437 - (15%)

Human    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVP 78
            :|.|.|::|.:.|.|.:|.|.| .|..| |..:.:.....:....|:.:.....||
  Fly     6 VVLDNGAHTAKVGLANQDEPHV-VPNCI-MKAKSERRRAFVGNQIDECRDTSALYY--------- 59

Human    79 RENMEAISPLKNGMVEDWDSFQAILDHTY-KMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFE 142
                  |...:.|.:.:|.:.:.:.|:.: |..:........::::|...|.::.:|...|::||
  Fly    60 ------ILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFE 118

Human   143 HYNIPAFFLCKTAVLTAF-----ANGRST-----GLILDSGATHTTAIPVHDGYVLQQGIVKSPL 197
            .|.:...:....|.|.||     :..|:|     .:|:|.|.:.|..:|...|..:.|||.:..:
  Fly   119 EYKVDGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDM 183

Human   198 AGDFITMQCRELFQEMNIELVPPYMIASK---------EAVREGSPANWKRKEKLPQVTRSWHNY 253
            .|..:|.|.:||....::.::....:.::         |..::....::. :||..:||..:
  Fly   184 GGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYS-EEKRREVTVDY--- 244

Human   254 MCNCVIQDF---QASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVK 315
                |:.||   :...::|.....:::...||.::         |:   ||..:||.||:||::
  Fly   245 ----VLPDFTTVKRGYVRVPGKPREDEEQQQMVSL---------CN---ERFTVPELLFNPSDI- 292

Human   316 GLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKL 380
               |...:|:...|...:..|..:....|..::::.||:.....|..||.|:|....|..:.:.|
  Fly   293 ---GVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSL 354

Human   381 IANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERK 427
            |.....|  |: :|.||..:|:...|::...::.:|||.|.|.:.::
  Fly   355 ICPEDPV--RY-AWYGGKEVATSPNFEEFVYTQDDYEEYGFQGINQR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTL6A	NP_004292.1	ASKHA_NBD_Arp4_ACTL6-like	8..420	CDD:466846	92/428 (21%)
Arp6	NP_511165.1	ASKHA_NBD_Arp6	5..391	CDD:466816	92/428 (21%)