DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment YHK8 and CG33282

DIOPT Version :9

Sequence 1:	NP_011914.1	Gene:	YHK8 / 856444	SGDID:	S000001090	Length:	514	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	112/491 - (22%)
Similarity:	192/491 - (39%)	Gaps:	103/491 - (20%)

- Green bases have known domain annotations that are detailed below.

Yeast    72 RYYISSLITFTSMVITM---ISSSWTLPSTHIIE------HFHIS-HEVSTLGITLYVFGLGIGP 126
            ||.:  |.|....:||.   :...|..|:...|:      .|.:: .::|.||..|.:..| .|.
  Fly    15 RYQL--LATVIVNIITFGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSL-CGN 76

Yeast   127 LFLSPLSELYGRRI-TFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFGSAFLSVAGGAIADI 190
            |.::.|.|..||:. .:|.|...:.|| .|...:..:..:...|||.||.|.|...|....|:::
  Fly    77 LTIAMLIERAGRKFCLYLMAGPYACIW-ILIYCASNVYYLYAARFLCGFTGGAGYLVVPIFISEV 140

Yeast   191 FDKDQIGIPMAIYTTSAFLGPSLGPIIGGAL-YHQSYKWTFITLLITSGCCLVMIIFTIPETYKP 254
            .|.:..|...::...|..||...|.|:...| ||..   .|:.:::.....:..|:  :||| .|
  Fly   141 ADSNIRGALTSMVMLSVDLGILAGYILSTYLAYHVV---PFLAIILPVAYFIANIM--LPET-AP 199

Yeast   255 MLLIRKAKRLRKEKNDQRYY-----AVLEVTRE------QTSLLS-----AIFLSTKRPFGLLLR 303
            .||  |..:|...:|..|||     |:.|.|.:      :|::||     |..||.|   .|..:
  Fly   200 YLL--KKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAVLSQQTRNATPLSYK---DLTTK 259

Yeast   304 DRMMGVLCFYTGLELAIIYLYFVAFPY------VFKKLYNFGPMEIACSYIGIMVGMILSAPTCL 362
            ..:.|   |...:.|::.|.:...|.:      :||...:...:..|...||::  .|:...|..
  Fly   260 PALKG---FAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLV--QIVGVYTST 319

Yeast   363 LFQKTFEWRVKRNNGVKTPEMRFEPLFYGAFLTPVGLFIFAFTCYKHV---------HWIAPIIG 418
            :.......||.         |....:       .||:...||.|:.::         :|: |::.
  Fly   320 ILVDIVGRRVL---------MLISTM-------GVGIGCIAFGCFTYLAKIYDLSDFNWL-PLVL 367

Yeast   419 SAIFG-------SGVYF-VFTGVFAYTVDAYRRYAASGMACNTFVRCIMAGVFPLFGLQMYKSMG 475
            ..|..       .|::| |...:|...:    |..|:.::. .|:..::.|...||.|.:: ..|
  Fly   368 MIIICYVANIGLIGIFFLVLVELFPVKI----RSLATSLSV-IFLSLLVFGTLKLFPLMLH-YWG 426

Yeast   476 VN---WAGFLLAMVTVAMIPVPFLFTKYGARLRAKS 508
            ::   |.....|::|.      |.|..:....:.||
  Fly   427 ISFTMWFSAASALLTF------FYFWLFLQETKGKS 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
YHK8	NP_011914.1	MFS_Tpo1_MDR_like	77..505	CDD:340881	108/481 (22%)
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	107/473 (23%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	91/395 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000