Protein Alignment TIF3 and eIF4B

DIOPT Version :9

• Sequence 1: NP_015489.1
• Gene: TIF3 / 856292
• SGDID: S000006367
• Length: 436
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 86/377 - (22%)
• Similarity: 137/377 - (36%)
• Gaps: 121/377 - (32%)

Yeast    91 EEYPVPDAPPYRAVINNIPWDITPEGVQAWVED-GLVKPEAVEEVVLPKNLRDPTRLKGNAFVTL 154
            ::..:|...|:.|.|||:|:|...:.:..:.|. .|:      .:.||:...:..|.:|..:|.|
  Fly    70 DDNSIPHKAPFIAYINNLPFDANEDDLYEFFEGINLI------SLRLPREDGENGRSRGFGYVEL 128

Yeast   155 KERADLVAVLKFNGTKLNERTVYVSVAAPRRGGGADVDWSSARGSNFQ-------GDGREDAPDL 212
            :.|.||:.||......:..|.:.:.::       .:.|..|.:.||.:       ||.|:..
  Fly   129 ENREDLIHVLSLPDPSIKGRRIRIELS-------NENDQQSRQKSNRRFDGFGNNGDNRDSG--- 183

Yeast   213 DWGAARGSNFRGPRREREEVDIDWTAARGSNFQGSSRPPRREREEVDIDWSAARGSNFQGSSRPP 277
            :|           ||:.:.        .||||..|                    |||:   |..
  Fly   184 NW-----------RRDSQN--------NGSNFGYS--------------------SNFE---RSF 206

Yeast   278 RREREE-PDIDWSAARGSNFQSSSRPPRREREEPDIDWSAARGSNFQSSSRPPRREREKEEPALD 341
            .|||:. ||.|.....|| :::|:||       ..||.|            |.|||.|:......
  Fly   207 NRERKSLPDRDDVNTPGS-WRTSARP-------QSIDTS------------PTRREVEQVSEKYR 251

Yeast   342 WGAARGAQFGKPQQTKNTYKDRSLTN-KKTTDEQPKIQKSVYDVLRTEDDDEDE-EAEKQNGDAK 404
            .|..:.|.....::|....::|...| |..|...|.::     .:..|..|.|| ..:||.|.:.
  Fly   252 EGRVKIADRYSREETSKVEEERPKLNLKPRTLPLPDVK-----TIEFEKCDVDEFNLDKQGGTSS 311

Yeast   405 EN------KVDAAVEKLQ---------------------DKTAQLTVEDGDN 429
            .|      .||.|..:|:                     :|.|:|.|:..||
  Fly   312 LNVFGSAKPVDTAARELEIEQRLALARKQDKGRREQGLNEKLAELQVDKNDN 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TIF3	NP_015489.1	RRM4_RBM12_like	102..179	CDD:409936	20/77 (26%)
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	63/273 (23%)
		RRM_eIF4B	79..155	CDD:240848	21/81 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105219
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1292
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840