Protein Alignment CDK10 and CDC28

DIOPT Version :9

• Sequence 1: XP_011521707.1
• Gene: CDK10 / 8558
• HGNCID: 1770
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_009718.3
• Gene: CDC28 / 852457
• SGDID: S000000364
• Length: 298
• Species: Saccharomyces cerevisiae
• Alignment Length: 338
• Identity: 123/338 - (36%)
• Similarity: 180/338 - (53%)
• Gaps: 67/338 - (19%)

Human    39 FEKLNRIGEGTYGIVYRARDT---QTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVE 100
            :::|.::||||||:||:|.|.   |...:|||||:|::.|.:|:|.:::|||:||..|:..|||.
Yeast     8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 72

Human   101 LKEVVVGNHLES--IFLVMGYCEQDLASLLENMP--TPFSEAQVKCIVLQVLRGLQYLHRNFIIH 161
            |.::|   |.::  ::||..:.:.||...:|.:|  .|.....||..::|:.:|:.|.|.:.|:|
Yeast    73 LYDIV---HSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILH 134

Human   162 RDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWVSK 226
            ||||..|||:...|.:|..|||||||:|||::..|.::|||||||||:|||....:|.:|.|
Yeast   135 RDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTW--- 196

Human   227 GLAAVRSSVPRAGGVSRRLAAVRSTVLCRAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPS 291
                                         ::|||.||:...:|:..|.|||.||..|.::||||:
Yeast   197 -----------------------------SIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPN 232

Human   292 ENIWPGFSKLPLVGQYSLRKQPYNNLKHKFP-W-----------LSEAGLRLLHFLFMYDPKKRA 344
            |.|||....||             :.|..|| |           |...|:.||..|..|||..|.
Yeast   233 EAIWPDIVYLP-------------DFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRI 284

Human   345 TAGDCLESSYFKE 357
            :|.......||:|
Yeast   285 SARRAAIHPYFQE 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK10	XP_011521707.1	STKc_CDK10	31..371	CDD:173742	123/338 (36%)
		PTZ00024	43..368	CDD:240233	122/334 (37%)
CDC28	NP_009718.3	STKc_CDK1_CdkB_like	8..295	CDD:270829	120/334 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910