Protein Alignment CDK10 and KIN28

DIOPT Version :9

• Sequence 1: XP_011521707.1
• Gene: CDK10 / 8558
• HGNCID: 1770
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_010175.1
• Gene: KIN28 / 851450
• SGDID: S000002266
• Length: 306
• Species: Saccharomyces cerevisiae
• Alignment Length: 328
• Identity: 116/328 - (35%)
• Similarity: 182/328 - (55%)
• Gaps: 35/328 - (10%)

Human    38 EFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELK 102
            |:.|..::|||||.:||......|...:|:|:::..:.|||:.:|::||:..|..::|||::||.
Yeast     6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELI 70

Human   103 EVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVS 167
            ::.:.  .:::.||:.:...||..::::....|:.|.:|..:|..|||:.:.|||||:|||||.:
Yeast    71 DIFMA--YDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPN 133

Human   168 NLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWVSKGLAAVR 232
            |||.:..|.:|.||||||||...|.:.:|..|||.||||||||.|....|::||:|
Yeast   134 NLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIW--------- 189

Human   233 SSVPRAGGVSRRLAAVRSTVLCRAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPG 297
                                   :||.|.|||:...|.|||.:::.|:::..:.||||::..||.
Yeast   190 -----------------------SVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPE 231

Human   298 FSKLPLVGQYSLRKQP-YNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLP 361
            .|......:..:...| .:.|:.:|...||..|..:..:...:|:||.||..||||.||||.|.|
Yeast   232 VSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP 296

Human   362 CEP 364
            .:|
Yeast   297 SDP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK10	XP_011521707.1	STKc_CDK10	31..371	CDD:173742	116/328 (35%)
		PTZ00024	43..368	CDD:240233	114/323 (35%)
KIN28	NP_010175.1	STKc_CDK7	7..302	CDD:270833	115/327 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910