Protein Alignment CDK10 and Pitslre

DIOPT Version :9

• Sequence 1: XP_011521707.1
• Gene: CDK10 / 8558
• HGNCID: 1770
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_649251.2
• Gene: Pitslre / 40292
• FlyBaseID: FBgn0016696
• Length: 952
• Species: Drosophila melanogaster
• Alignment Length: 364
• Identity: 173/364 - (47%)
• Similarity: 231/364 - (63%)
• Gaps: 47/364 - (12%)

Human    33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 97
            ||||:||:.||||.|||||:||||:|.:|:||||||:::|:|||:|.||:|||||..||:.:|||
  Fly   552 CRSVEEFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPN 616

Human    98 IVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT---PFSEAQVKCIVLQVLRGLQYLHRNFI 159
            ||.::|:|||::::.||:||.|.|.||.||:|.|..   .|...:|||:..|:||.:.:||.|:|
  Fly   617 IVTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWI 681

Human   160 IHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWV 224
            :|||||.||||::.||.:|..||||||.||.|:|..|..|||||||||||||.:...:|.||:|
  Fly   682 LHRDLKTSNLLLSHKGILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDVW- 745

Human   225 SKGLAAVRSSVPRAGGVSRRLAAVRSTVLCRAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGT 289
                                           :||||.||.|...||.||.|||.:::.|.:.|||
  Fly   746 -------------------------------SVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGT 779

Human   290 PSENIWPGFSKLPLV-------GQYSLRKQPYNNL-KHKFPWLSEAGLRLLHFLFMYDPKKRATA 346
            |:|.||||:::||.|       .|::  :.|.:.| ||.....||.||.||..|..||||:|.:|
  Fly   780 PNEKIWPGYTELPAVKNMLSQNSQFT--EYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSA 842

Human   347 GDCLESSYFKEKPLPCEPELMPTFP--HHRNKRAAPATS 383
            ...|:..:|||.|||.:|.:.||:|  .....|.|.|:|
  Fly   843 DAALKHGFFKELPLPIDPSMFPTWPAKSELGARKAQASS 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK10	XP_011521707.1	STKc_CDK10	31..371	CDD:173742	168/348 (48%)
		PTZ00024	43..368	CDD:240233	159/335 (47%)
Pitslre	NP_649251.2	STKc_CDC2L1	552..851	CDD:173741	159/332 (48%)
		PLN00009	555..854	CDD:177649	158/332 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0663
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D392617at33208
OrthoFinder	1	1.000	-	-		FOG0001516
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R970
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850