Protein Alignment SCRT2 and esg

DIOPT Version :10

• Sequence 1: NP_149120.1
• Gene: SCRT2 / 85508
• HGNCID: 15952
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_476600.1
• Gene: esg / 34903
• FlyBaseID: FBgn0287768
• Length: 470
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 120/351 - (34%)
• Similarity: 154/351 - (43%)
• Gaps: 75/351 - (21%)

Human    20 VPAPTY-------------------------H---PLETAYVLP-------GARGPPGD---NGY 46
            ||.|||                         |   ||....:.|       |:..||..   :|.
  Fly   120 VPTPTYPKYPWNNFHMSPYTAEFYRTINQQGHQILPLRGDLIAPSSPSDSLGSLSPPPHHYLHGR 184

Human    47 APHRLPPSSYDADQKP-GLEL-----APAEPAYP-------------PAAPEEYSDPESPQSSLS 92
            |....||...:...:| |:..     .|..|.||             |.:| .||:    .|..|
  Fly   185 ASSVSPPMRSEIIHRPIGVRQHRFLPYPQMPGYPSLGGYTHTHHHHAPISP-AYSE----NSYYS 244

Human    93 ARYFRGEAAVTDSYSMDAFFISDGRSRRRRGGGGGD--AGGSGDAGGAGGRAGRAGAQAGGGHRH 155
            .|....|::.:.|...|........:........|:  |..:||..........|........|:
  Fly   245 MRSMTPESSCSSSLPEDLSLKHKNLNLNLNTSQPGEQAAAKTGDMSPETMPNASAKKDKNQPPRY 309

Human   156 ACAECGKTYATSSNLSRHKQTH-RSLDSQLARK---CPTCGKAYVSMPALAMHLLTHNLRHKCGV 216
            .|.:|.|:|:|.|.|::|:|.| .:.:....:|   |..|.|.|||:.||.||:.||.|..||.:
  Fly   310 QCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSFSCKDCDKTYVSLGALKMHIRTHTLPCKCNL 374

Human   217 CGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKS 281
            ||||||||||||||:|:|||||||.|.||.:|||||||||||:||||..|.|.|..|.|:|:..|
  Fly   375 CGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFADRSNLRAHLQTHSDIKKYSCTSCSKTFSRMS 439

Human   282 YLHKHCEAACAKAAEPPPPTPAGPAS 307
            .|.||.|..|       |...||.:|
  Fly   440 LLTKHSEGGC-------PGGSAGSSS 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCRT2	NP_149120.1	SNAG domain. /evidence=ECO:0000250	1..20		120/351 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..90		18/84 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..148		5/33 (15%)
		C2H2 Zn finger	157..177	CDD:275368	9/19 (47%)
		zf-C2H2	212..234	CDD:395048	17/21 (81%)
		C2H2 Zn finger	214..234	CDD:275368	16/19 (84%)
		zf-H2C2_2	227..250	CDD:463886	16/22 (73%)
		C2H2 Zn finger	242..262	CDD:275368	15/19 (79%)
		zf-C2H2	242..262	CDD:395048	15/19 (79%)
		zf-H2C2_2	254..278	CDD:463886	14/23 (61%)
		C2H2 Zn finger	270..286	CDD:275368	6/15 (40%)
esg	NP_476600.1	KREPA	<278..>329	CDD:483960	14/50 (28%)
		zf-C2H2	309..331	CDD:395048	9/21 (43%)
		C2H2 Zn finger	311..331	CDD:275370	9/19 (47%)
		zf-C2H2	344..366	CDD:395048	10/21 (48%)
		C2H2 Zn finger	346..366	CDD:275368	10/19 (53%)
		zf-C2H2	370..392	CDD:395048	17/21 (81%)
		C2H2 Zn finger	372..392	CDD:275368	16/19 (84%)
		zf-H2C2_2	385..408	CDD:463886	16/22 (73%)
		zf-C2H2	398..420	CDD:395048	16/21 (76%)
		C2H2 Zn finger	400..420	CDD:275368	15/19 (79%)
		C2H2 Zn finger	428..444	CDD:275368	6/15 (40%)