DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HXT2 and CG33282

DIOPT Version :9

Sequence 1:	NP_013724.1	Gene:	HXT2 / 855023	SGDID:	S000004613	Length:	541	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	132/530 - (24%)
Similarity:	219/530 - (41%)	Gaps:	125/530 - (23%)

- Green bases have known domain annotations that are detailed below.

Yeast    32 SPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFG-GFVFGWDTGTISGFVNQT-----DFKRRF 90
            |.:|.|:.|   :|.|       |||  ..:|.|| |...||.:.|::..  ||     ||:...
  Fly     8 SLLQQKTRY---QLLA-------TVI--VNIITFGHGVGVGWLSPTLTKI--QTADSPLDFEVNL 58

Yeast    91 GQMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVY-IVGIVIQIAS 154
            .|:.     :|     |.::|:.:: |  |.||:..|.:..||:..|..:...| .:.|:|..||
  Fly    59 AQIS-----WL-----GSMLGLDSL-C--GNLTIAMLIERAGRKFCLYLMAGPYACIWILIYCAS 110

Yeast   155 SDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKD 219
            :  .|..:..|.:.|...|...::.|..|||.|..:|||...|...|.:.|||..||.
  Fly   111 N--VYYLYAARFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYI------- 166

Yeast   220 YSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSL-----------AKSNKV 273
            .|..:.:.|...|.....:......:|:||:..:|::|.:...|:.|.           .:::||
  Fly   167 LSTYLAYHVVPFLAIILPVAYFIANIMLPETAPYLLKKSQLAAAENSFRYYRNQRSAICEQTSKV 231

Yeast   274 TIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYG 338
            ..|      |:.|.:.:.:| |.|...|:.:| :.|.| |......|::....|.:|...|..|.
  Fly   232 NFE------ELRTAVLSQQT-RNATPLSYKDL-TTKPA-LKGFAASIVLSLGYQFSGVFSFINYM 287

Yeast   339 TTIFNAVG-MKDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTS 402
            :.||.|.| :.|....:|::|:|.....:.:...||..|||..:|            .||:||
  Fly   288 SDIFKASGSVVDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLML------------ISTMGV-- 338

Yeast   403 LYPNGKDQPSSKAAGNVMIVFTCLFIFFFAI------SWAP-----------------IAYVIVA 444
                          |...|.|.| |.:...|      :|.|                 |.::::.
  Fly   339 --------------GIGCIAFGC-FTYLAKIYDLSDFNWLPLVLMIIICYVANIGLIGIFFLVLV 388

Yeast   445 ESYPLRVKNRAMAIAVGANWIWGFLIGFFT----PFITSAIGFSYGYVFMGC-LVFSFFYVFFFV 504
            |.:|:::::.|.:::|    |:..|:.|.|    |.:....|.|:...|... .:.:|||.:.|:
  Fly   389 ELFPVKIRSLATSLSV----IFLSLLVFGTLKLFPLMLHYWGISFTMWFSAASALLTFFYFWLFL 449

Yeast   505 CETKGLTLEE 514
            .||||.::.|
  Fly   450 QETKGKSMIE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HXT2	NP_013724.1	Sugar_tr	59..519	CDD:395036	123/503 (24%)
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	120/494 (24%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	98/419 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.830