Protein Alignment GFM1 and gfm1

DIOPT Version :10

• Sequence 1: NP_001295093.1
• Gene: GFM1 / 85476
• HGNCID: 13780
• Length: 770
• Species: Homo sapiens
• Sequence 2: NP_001073463.1
• Gene: gfm1 / 561840
• ZFINID: ZDB-GENE-061013-79
• Length: 745
• Species: Danio rerio
• Alignment Length: 770
• Identity: 584/770 - (75%)
• Similarity: 675/770 - (87%)
• Gaps: 25/770 - (3%)

Human     1 MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTER 65
            ||||.||  ::|.|...|.....|:..:   :||..|:|:.|||:||||||||||||||||||||
Zfish     1 MRLLRAA--SSLARLHRPGHSTLQQVLI---SCRSCSNGITPNERIRNIGISAHIDSGKTTLTER 60

Human    66 VLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIE 130
            |||||||||:||||:|||||||:||||||||||||||||||||||||:.||||||||||||||||
Zfish    61 VLYYTGRIAEMHEVRGKDGVGAIMDSMELERQRGITIQSAATYTMWKNHNINIIDTPGHVDFTIE 125

Human   131 VERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARALQQMRSKLN 195
            |||:|||||||||||||||||||||:|||||||||:||||||||||||:|:||.|||||:|:|||
Zfish   126 VERSLRVLDGAVLVLCAVGGVQCQTVTVNRQMKRYSVPFLTFINKLDRLGANPNRALQQLRTKLN 190

Human   196 HNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGHFLRDFLPLLWNWDRRSGSQIVRYGEIPAE 260
            .||||:.||:|||||.:||:||||||:|.|||.||                   :.|||.:||.|
Zfish   191 QNAAFVNIPIGLEGNLRGIIDLIEERSIVFDGPFG-------------------ESVRYEDIPPE 236

Human   261 LRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGV 325
            :|:.|.|.||||:|||||:||.||||||||::|::.|||.|:||||:||||:||.:|||||||||
Zfish   237 MRSEAADRRQELVECVANADETLGEMFLEERVPTVLDLKAAVRRATVKRSFSPVLVGSALKNKGV 301

Human   326 QPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKLEVGRFGQLTYV 390
            ||||||||||||||:|||||||||:|.:| |.:||||:|:||::.||||||||||.|||||||||
Zfish   302 QPLLDAVLEYLPNPTEVQNYAILNEEGES-EGSKILMDSTRDDTQPFVGLAFKLEAGRFGQLTYV 365

Human   391 RSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKAN 455
            |.|||.|:|.|.|:|:||.::||:|||.|:|||.|||||..||||||||||||||||||||.:.|
Zfish   366 RVYQGCLRKTDYIHNSRTGRRVRVQRLVRLHADQMEDVEVAYAGDICALFGIDCASGDTFTARNN 430

Human   456 SGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHL 520
            :.|||||||||:||||:|::||||||.:|.||||.|||||||||:|:||||:|||:|||||||||
Zfish   431 ANLSMESIHVPEPVISMAIRPSNKNDTDKLSKGISRFTREDPTFRVHFDTESKETIISGMGELHL 495

Human   521 EIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPEDYTK 585
            |||:||:||||.|||:.||||||||||:|:.|||::||||||||:||||||||||||||.|:|||
Zfish   496 EIYSQRMEREYSCPCVMGKPKVAFRETLTSAVPFEYTHKKQSGGSGQYGKVIGVLEPLDSENYTK 560

Human   586 LEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAGE 650
            :||||||.|:||||||||||||||.||||||||.|||:||:||||:|||||||||||||||||||
Zfish   561 VEFSDETVGTNIPKQFVPAVEKGFRDACEKGPLIGHKISGVRFVLEDGAHHMVDSNEISFIRAGE 625

Human   651 GALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLYADVPLNDM 715
            ||:||||..||:.||||:|:||:||||||||.||||:|||||||:||||.:.|||||||:|||||
Zfish   626 GAVKQALEKATVVILEPVMSVEIVAPNEFQGAVIAGVNRRHGVISGQDGADGYFTLYADIPLNDM 690

Human   716 FGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEATGQLPVKKGKAKN 770
            |||:|||||||||||||||||||||||..|.|||::||:||||||||.||.|.||
Zfish   691 FGYATELRSCTEGKGEYTMEYSRYQPCAASVQEDLVNKHLEATGQLPAKKSKWKN 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFM1	NP_001295093.1	FusA	39..754	CDD:440248	557/714 (78%)
gfm1	NP_001073463.1	FusA	36..729	CDD:440248	556/712 (78%)