Protein Alignment GFM1 and Gfm1

DIOPT Version :10

• Sequence 1: NP_001295093.1
• Gene: GFM1 / 85476
• HGNCID: 13780
• Length: 770
• Species: Homo sapiens
• Sequence 2: NP_613057.2
• Gene: Gfm1 / 28030
• MGIID: 107339
• Length: 751
• Species: Mus musculus
• Alignment Length: 773
• Identity: 683/773 - (88%)
• Similarity: 716/773 - (92%)
• Gaps: 25/773 - (3%)

Human     1 MRLLGAAAVAALGRG---RAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTL 62
            ||||..|  ||||||   |.||.||||.||.:||..||.|||.:|||||||||||||||||||||
Mouse     1 MRLLRVA--AALGRGPFPRVPAVLGWQGKQADWKTRRWCSSGPVPNEKIRNIGISAHIDSGKTTL 63

Human    63 TERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDF 127
            ||||||||||||.||||||||||||||||||||||||||||||||||||||:|||||||||||||
Mouse    64 TERVLYYTGRIATMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDININIIDTPGHVDF 128

Human   128 TIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARALQQMRS 192
            |||||||||||||||||||||||||||||||:||||||||||||||||||||||||:||||||||
Mouse   129 TIEVERALRVLDGAVLVLCAVGGVQCQTMTVSRQMKRYNVPFLTFINKLDRMGSNPSRALQQMRS 193

Human   193 KLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGHFLRDFLPLLWNWDRRSGSQIVRYGEI 257
            ||||||||:|||:||||:||||:|||||||||||||||                   |||||.||
Mouse   194 KLNHNAAFVQIPIGLEGDFKGIIDLIEERAIYFDGDFG-------------------QIVRYDEI 239

Human   258 PAELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSALKN 322
            ||.|||||.|||||||||||||||||||:||||||||:||||.|||||||.||||||||||||||
Mouse   240 PAGLRAAAADHRQELIECVANSDEQLGELFLEEKIPSVSDLKRAIRRATLSRSFTPVFLGSALKN 304

Human   323 KGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKLEVGRFGQL 387
            ||||||||||||||||||||||||||| ::|||||||||||..||:||||||||||||.||||||
Mouse   305 KGVQPLLDAVLEYLPNPSEVQNYAILN-QNDSKEKTKILMNPQRDDSHPFVGLAFKLEAGRFGQL 368

Human   388 TYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTD 452
            ||||:||||||||.|||||||.||||:|||.|||||||||||||||||||||||||||||||||:
Mouse   369 TYVRNYQGELKKGSTIYNTRTGKKVRVQRLVRMHADMMEDVEEVYAGDICALFGIDCASGDTFTN 433

Human   453 KANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGE 517
            |.||.|||||||||:|||||||:||||||||||||||||||||||||||:||.|:|||::|||||
Mouse   434 KDNSDLSMESIHVPEPVISIAMRPSNKNDLEKFSKGIGRFTREDPTFKVHFDPESKETIVSGMGE 498

Human   518 LHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPED 582
            |||||||||:|||||||||||||||||||||.||||||||||||||||||:||||||||||.|||
Mouse   499 LHLEIYAQRMEREYGCPCITGKPKVAFRETIVAPVPFDFTHKKQSGGAGQFGKVIGVLEPLPPED 563

Human   583 YTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIR 647
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   564 YTKLEFSDETFGSNVPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIR 628

Human   648 AGEGALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLYADVPL 712
            ||||||||||||.||||:||||:|||:|||||||.|.|||||||||||||||:||||||||||||
Mouse   629 AGEGALKQALANGTLCIIEPIMSVEVIAPNEFQGTVFAGINRRHGVITGQDGIEDYFTLYADVPL 693

Human   713 NDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEATGQLPVKKGKAKN 770
            |:||||||||||||||||||||||.|||||.|||||::||||||||||||||||||||
Mouse   694 NNMFGYSTELRSCTEGKGEYTMEYCRYQPCSPSTQEELINKYLEATGQLPVKKGKAKN 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFM1	NP_001295093.1	FusA	39..754	CDD:440248	639/714 (89%)
Gfm1	NP_613057.2	FusA	45..735	CDD:440248	636/709 (90%)