Protein Alignment GFM1 and gfm1

DIOPT Version :10

• Sequence 1: NP_001295093.1
• Gene: GFM1 / 85476
• HGNCID: 13780
• Length: 770
• Species: Homo sapiens
• Sequence 2: XP_002933285.1
• Gene: gfm1 / 100494046
• XenbaseID: XB-GENE-983072
• Length: 748
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 618/779 - (79%)
• Similarity: 681/779 - (87%)
• Gaps: 40/779 - (5%)

Human     1 MRLLGAAAVAALGRGRAPASLGWQ---------RKQVNWKACRWSSSGVIPNEKIRNIGISAHID 56
            ||||           |..:.||.|         .|.:....||:.|||::|||:|||||||||||
 Frog     1 MRLL-----------REASKLGSQALRYSGITRNKPLPLTFCRYCSSGIVPNERIRNIGISAHID 54

Human    57 SGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDT 121
            ||||||||||||||||||:||||||||||||||||||||||||||||||||||||||.|||||||
 Frog    55 SGKTTLTERVLYYTGRIAQMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDTNINIIDT 119

Human   122 PGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARA 186
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||.||
 Frog   120 PGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRLGSNPNRA 184

Human   187 LQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGHFLRDFLPLLWNWDRRSGSQI 251
            :||:||||||||||:|||:|:|..||||:||:||||:||||:||                   |.
 Frog   185 VQQLRSKLNHNAAFVQIPIGIESKFKGIIDLVEERAMYFDGEFG-------------------QT 230

Human   252 VRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFL 316
            :||.:||||.||.|.|.||||||.||||||.|||||||||||::||||||||||||||.||||.:
 Frog   231 MRYEDIPAEFRAEAMDRRQELIESVANSDEILGEMFLEEKIPTVSDLKLAIRRATLKRLFTPVLV 295

Human   317 GSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKLEV 381
            |||||||||||||:||||||||||||||:||||.| :|:|.|||||||.||:|.||||||||||.
 Frog   296 GSALKNKGVQPLLEAVLEYLPNPSEVQNFAILNHE-NSEEATKILMNSVRDSSQPFVGLAFKLEA 359

Human   382 GRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCAS 446
            ||||||||||.|||.|:|.|.|:||||.||||:|||.|:||||||||||.|||||||||||||||
 Frog   360 GRFGQLTYVRVYQGMLQKSDYIFNTRTGKKVRVQRLVRLHADMMEDVEEAYAGDICALFGIDCAS 424

Human   447 GDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETV 511
            |||||.|:|..||||||||||||||:||||:|||||:||||||.|||||||||:|:::.|:|||:
 Frog   425 GDTFTSKSNDNLSMESIHVPDPVISVAMKPTNKNDLDKFSKGISRFTREDPTFRVHYEVESKETI 489

Human   512 ISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLE 576
            |||||||||||||||:||||.|||:.|||||||||||:..||||||||||||||||||||||.||
 Frog   490 ISGMGELHLEIYAQRMEREYACPCVMGKPKVAFRETISKTVPFDFTHKKQSGGAGQYGKVIGFLE 554

Human   577 PLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSN 641
            ||:.|:||||||.|:|.|:|:|||||||||:||.:|||||||:|||:|||||||:||||||||||
 Frog   555 PLEAENYTKLEFEDKTVGTNVPKQFVPAVERGFREACEKGPLTGHKISGLRFVLEDGAHHMVDSN 619

Human   642 EISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTL 706
            |||||||||||||||:.|||:|||||||:||||||:||||.||||||||||||.||||.|.||||
 Frog   620 EISFIRAGEGALKQAMENATVCILEPIMSVEVVAPSEFQGPVIAGINRRHGVIVGQDGSEGYFTL 684

Human   707 YADVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEATGQLPVKKGKAKN 770
            ||||||||||||::|||||||||||||||||||||||.||||::||||||||||||.||||||:
 Frog   685 YADVPLNDMFGYASELRSCTEGKGEYTMEYSRYQPCLASTQEELINKYLEATGQLPAKKGKAKS 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GFM1	NP_001295093.1	FusA	39..754	CDD:440248	589/714 (82%)
gfm1	XP_002933285.1	FusA	42..732	CDD:440248	586/709 (83%)