Protein Alignment LBX2 and Dr

DIOPT Version :10

• Sequence 1: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 61/200 - (30%)
• Similarity: 82/200 - (41%)
• Gaps: 56/200 - (28%)

Human     3 SGREPRTPR----------TLLSIADILAPRMVPRAPSAPQLPESGPGPTSPLCALEELTSKTFR 57
            ||:...:|.          |:||.| .||...||..|:          |.|.|.|    .:..:.
  Fly   324 SGKSLESPHGPPPGSHMQSTILSPA-ALASGHVPIRPT----------PFSALAA----AAVAWT 373

Human    58 GLDARALQPSEGRA---GPDALGPGP-FG----------------RKRRKSRTAFTAQQVLELER 102
            |:......|...:.   ||..:.||. ||                :..||.||.||.||:|.||:
  Fly   374 GMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEK 438

Human   103 RFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVLCSLAL 167
            :|..::||:.:||...::.|.|...||..||||||||.||           |:....|.:...||
  Fly   439 KFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKR-----------LQEAEIEKIKMAAL 492

Human   168 PEGAP 172
            ..|||
  Fly   493 GRGAP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		9/45 (20%)
		Homeodomain	86..142	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		60/199 (30%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	28/55 (51%)