Protein Alignment LBX2 and ro

DIOPT Version :10

• Sequence 1: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Sequence 2: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 197
• Identity: 56/197 - (28%)
• Similarity: 82/197 - (41%)
• Gaps: 42/197 - (21%)

Human    22 PRMVPRAPSAPQLPESGPG--PTSPLCALEELTSKTFRGLDARALQPSEGRAGPDALGPGPFGRK 84
            |.:.....:.|.||.:.|.  |:.|      ..|..|....||. :..|||
  Fly   147 PAIAAGGAANPVLPHAFPAGFPSDP------HFSAGFSAFLARR-RRKEGR-------------- 190

Human    85 RRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRA 149
            :|:.||.|:.:|.|.||..|...:|::.|.|..||..|.|...|:..||||||||.|| :|:.:.
  Fly   191 QRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKR-IEKAQI 254

Human   150 D-------VASLRALSPEVLCSLALPEGAPDPGLCLG--------PAGPDSRPHLSDEE---IQV 196
            |       ||:....|.....:..:|.|....|:.:|        .|.|.:.|..:.::   |.:
  Fly   255 DQHYRNFVVANGFMSSIMGQAATTMPPGGVTGGVAVGVGLNYYAAAATPAALPKDNTQDANFIDI 319

Human   197 DD 198
            ||
  Fly   320 DD 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		6/23 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		4/25 (16%)
		Homeodomain	86..142	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		6/35 (17%)
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	23/51 (45%)