Protein Alignment LBX2 and Dbx

DIOPT Version :10

• Sequence 1: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 211
• Identity: 64/211 - (30%)
• Similarity: 81/211 - (38%)
• Gaps: 57/211 - (27%)

Human    26 PRAPSAPQLPE-SGPGPTSPLCAL-EELTSKTFRGLDARALQP--SEGRAGPDALGPG---PF-- 81
            |..|..|..|. :.|.|:.|...| ..|.......|.|....|  |.| |....|.||   |:
  Fly   362 PTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVG-AQVFPLPPGQGFPWAH 425

Human    82 ---GRKRR--KSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLK 141
               |:.||  ..|..|:..|...||:||..|||::..:|..||.||||.::||..||||||.|.:
  Fly   426 STRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWR 490

Human   142 R-------------------------DVEEMRADVASLRALSPEVLCSLALPEGA---PDPG--- 175
            .                         |:.:.:.| ..|..|||    ||..|.|:   |.||
  Fly   491 NSKERELLASGGSRDQTLPNKNNPNPDLSDAKCD-RPLTPLSP----SLLSPNGSATPPPPGAVA 550

Human   176 ------LCLGPAGPDS 185
                  ..:.|..|.|
  Fly   551 KDEPPTAAVTPKSPQS 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		7/20 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		11/37 (30%)
		Homeodomain	86..142	CDD:459649	27/57 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		5/22 (23%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	26/53 (49%)