Protein Alignment LBX2 and cad

DIOPT Version :10

• Sequence 1: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 180
• Identity: 49/180 - (27%)
• Similarity: 71/180 - (39%)
• Gaps: 43/180 - (23%)

Human    26 PRAPSAPQLPESGPGPTSPLCALEELTSKTFRGLDARALQPSEGRAGPDALGPGPFGRKRRKSRT 90
            |..|:.|| |:....|.     ||:|:..    |||      .|:.           |.:.|.|.
  Fly   259 PAYPAQPQ-PDLSSSPN-----LEDLSDL----LDA------SGKT-----------RTKDKYRV 296

Human    91 AFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRD-----------V 144
            .:|..|.||||:.:...:|:....:..||..|.|:..||..||||||||.::.           |
  Fly   297 VYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGV 361

Human   145 EEMRADVASL----RALSPEVLCSLALPEGAPDPGLCLGPAGPDSRPHLS 190
            ....||.:.|    ..|.|.:..|.:|.. :.:|...:........|||:
  Fly   362 GVQHADYSQLLDAKAKLEPGLHLSHSLAH-SMNPMAAMNIPAMRLHPHLA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		3/25 (12%)
		Homeodomain	86..142	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		4/18 (22%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)