DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment LBX2 and bsh

DIOPT Version :10

Sequence 1:NP_001269359.1 Gene:LBX2 / 85474 HGNCID:15525 Length:198 Species:Homo sapiens
Sequence 2:NP_477350.2 Gene:bsh / 35266 FlyBaseID:FBgn0000529 Length:429 Species:Drosophila melanogaster


Alignment Length:219 Identity:69/219 - (31%)
Similarity:92/219 - (42%) Gaps:55/219 - (25%)


- Green bases have known domain annotations that are detailed below.


Human     1 MNSGREPRTPRTLLSIADILAPRMVPRAPSAPQLPESGPG-------PTSPLC--ALEELT---- 52
            :.||.....|          .|...|:.|..|.| ..|.|       |.:|..  ...::|    
  Fly   169 LGSGAAQHPP----------VPTTQPQPPPPPPL-NGGSGASNGVLYPNAPYTDHGFLQMTLGYL 222

Human    53 ---SKTFRGLDARALQ--------PSEGRAG--PD-ALGPGPFG------RKRRKSRTAFTAQQV 97
               |.|::.:|...|.        |..|..|  |: |||.| .|      .:|||:||.|:..|:
  Fly   223 SPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLG-MGVNALRHCRRRKARTVFSDPQL 286

Human    98 LELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVL 162
            ..||:||..|:||:..||..|||.|||:..||.|||||||.|.|:.:.  |.|.|:    .|   
  Fly   287 SGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLR--RRDNAN----EP--- 342

Human   163 CSLALPEGAPDPGLCLGPAGPDSR 186
            ...:..|....||.....:| ||:
  Fly   343 VDFSRSEPGKQPGEATSSSG-DSK 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LBX2NP_001269359.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..46 8/28 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..89 13/42 (31%)
Homeodomain 86..142 CDD:459649 31/55 (56%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..198 5/14 (36%)
bshNP_477350.2 Homeodomain 275..331 CDD:459649 31/55 (56%)

Return to query results.
Submit another query.