Protein Alignment LBX2 and H2.0

DIOPT Version :10

• Sequence 1: NP_001269359.1
• Gene: LBX2 / 85474
• HGNCID: 15525
• Length: 198
• Species: Homo sapiens
• Sequence 2: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 173
• Identity: 51/173 - (29%)
• Similarity: 68/173 - (39%)
• Gaps: 40/173 - (23%)

Human     8 RTPRTLLSIADILAPRMVPRAPSAPQLPESGPGPTSPLCALEELTSKTFRGLDARALQPSEGRAG 72
            :||:.||.||                       ||||..|..           |.:...:.|..|
  Fly   248 KTPQQLLDIA-----------------------PTSPAAAAA-----------ATSQNGAHGHGG 278

Human    73 PDALGPGPFG----RKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWF 133
            .:..|....|    |||..||..|:..|...||.:|..|||:...:|..||.||.|.:|||..||
  Fly   279 GNGQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWF 343

Human   134 QNRRAKLKRDVEEMRADVASLRALSPEV--LCSLALPEGAPDP 174
            ||||.|.:...|.:::......:..||.  :...:.|.|...|
  Fly   344 QNRRMKWRHTRENLKSGQEKQPSAVPESGGVFKTSTPSGDGTP 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBX2	NP_001269359.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		4/21 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..89		7/29 (24%)
		Homeodomain	86..142	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..198		1/2 (50%)
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	29/59 (49%)