DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BI3 and CYTB

DIOPT Version :9

Sequence 1:	NP_009317.1	Gene:	BI3 / 854605	SGDID:	S000007272	Length:	517	Species:	Saccharomyces cerevisiae
Sequence 2:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	106/221 - (47%)
Similarity:	150/221 - (67%)	Gaps:	13/221 - (5%)

- Green bases have known domain annotations that are detailed below.

Yeast     4 RKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHI 68
            |.|:....:.|:.::|.|.|.:|:.|||.||||||||:|||:||:|:||||:::|.|||.||.||
  Fly     6 RNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHI 70

Yeast    69 MRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYR-SPRVTLWNVGVIIFILTIATAFLGY 132
            .|||:.|::||.||||||||||:.:::|:.:|:|||||: :|   .|.:||||..|.:.|||:||
  Fly    71 CRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTP---TWLIGVIILFLVMGTAFMGY 132

Yeast   133 CCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFNMEDPYYSNMMLNKSVLCWNIFIWMMNY 197
            ...:||||.|||||||||.||||::|.|:|.||||||.:::...:.......:|.:.:....|
  Fly   133 VLPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTM-- 195

Yeast   198 YIIQLIIY-----NNMIWNKNNMVKM 218
              |.|:..     ||.|...:|:.|:
  Fly   196 --IHLLFLHQTGSNNPIGLNSNIDKI 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BI3	NP_009317.1	Cytochrome_b_N	8..174	CDD:238176	95/166 (57%)
		LAGLIDADG_1	270..367	CDD:279328
		LAGLIDADG_1	405..499	CDD:279328
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	104/215 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346805
Domainoid	1	1.000	248	1.000	Domainoid score	I350
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1779
TreeFam	0	0.000	Not matched by this tool.
	5	4.940