DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZCRB1 and NOP13

DIOPT Version :9

Sequence 1:	NP_149105.3	Gene:	ZCRB1 / 85437	HGNCID:	29620	Length:	217	Species:	Homo sapiens
Sequence 2:	NP_014224.2	Gene:	NOP13 / 855547	SGDID:	S000005119	Length:	403	Species:	Saccharomyces cerevisiae

Alignment Length:	142	Identity:	36/142 - (25%)
Similarity:	64/142 - (45%)	Gaps:	9/142 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     7 PSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAI 71
            |....::|.||.|.:|::.|.:.|...|.:||:.:...:|:.|.||.|||.|.:::.:.|..:..
Yeast   236 PPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDK 300

Human    72 NNKQLFGRVIKASIAIDNG-----RAAEFIRRRN--YFD--KSKCYECGESGHLSYACPKNMLGE 127
            :.:::.||.::.....|..     :..|.:.|.|  .||  .:|.|:.....:.|....|.....
Yeast   301 SCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSSFDISNNKGYDRAGQDNGSKPEYKRSNAN 365

Human   128 REPPKKKEKKKK 139
            |.||.....:.|
Yeast   366 RRPPVDSNNRTK 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZCRB1	NP_149105.3	RRM_ZCRB1	9..86	CDD:240839	21/76 (28%)
		AIR1	<97..123	CDD:331526	7/29 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	120..217		5/20 (25%)
NOP13	NP_014224.2	RRM1_Nop13p_fungi	127..217	CDD:409830
NOP13	NP_014224.2	RRM2_Nop13p_fungi	241..316	CDD:409831	21/74 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910