DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZCRB1 and SNP1

DIOPT Version :9

Sequence 1:	NP_149105.3	Gene:	ZCRB1 / 85437	HGNCID:	29620	Length:	217	Species:	Homo sapiens
Sequence 2:	NP_012203.1	Gene:	SNP1 / 854749	SGDID:	S000001323	Length:	300	Species:	Saccharomyces cerevisiae

Alignment Length:	195	Identity:	47/195 - (24%)
Similarity:	83/195 - (42%)	Gaps:	11/195 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    11 TVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQ 75
            |:::..||:.|...:|.:.|.|:|::.|:.|:|||.|:||||.|||:|.|..|::...:.|...:
Yeast   108 TIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHR 172

Human    76 LFGRVIKASIA---IDNGRAAEFIRRRNYFD--KSKCYECGES---GHLSYACPKNMLGEREPPK 132
              |..||..|.   |:.||..::.:.|....  ..:.|...:|   |..:.|...|.......|:
Yeast   173 --GIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGRGYSNRDSRLPGRFASASTSNPAERNYAPR 235

Human   133 KKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGVPSTSDD 197
            ...::....|...:.......::...|..|.|.:.:...|.... .:....:.:.|...|..:.|
Yeast   236 LPRRETSSSAYSADRYGSSTLDARYRGNRPLLSAATPTAAVTSV-YKSRNSRTRESQPAPKEAPD 299

Human 198 197
Yeast 300 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZCRB1	NP_149105.3	RRM_ZCRB1	9..86	CDD:240839	28/74 (38%)
		AIR1	<97..123	CDD:331526	5/30 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	120..217		10/78 (13%)
SNP1	NP_012203.1	U1snRNP70_N	6..95	CDD:403437
SNP1	NP_012203.1	RRM_SNP1_like	89..201	CDD:410194	33/94 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910