DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BAG7 and cv-c

DIOPT Version :9

Sequence 1:	NP_014777.3	Gene:	BAG7 / 854302	SGDID:	S000005660	Length:	409	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001097786.1	Gene:	cv-c / 41749	FlyBaseID:	FBgn0285955	Length:	2351	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	61/246 - (24%)
Similarity:	106/246 - (43%)	Gaps:	43/246 - (17%)

- Green bases have known domain annotations that are detailed below.

Yeast    44 DGKVFGVSLEESLKVAQEEVIIQKSTNEIGSIPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRE 108
            |.|||||.|         .:|:|:|..   ::|:.:..:.::|:.||||..||||.:|...|:.:
  Fly  1893 DKKVFGVPL---------LMILQRSGQ---TLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMK 1945

Yeast   109 LQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRNPILENPKINEH-- 171
            |:.............:.:.....:|:|.:||:|...|.|.|:...:.:.|       ..|.:|
  Fly  1946 LREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETF-------VAIFQHLP 2003

Yeast   172 KEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLL--------- 227
            .|..:...:...:|||.:||.::..|...|.:.|.|.::|.|:::||...:..|:.
  Fly  2004 AEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSA 2068

Yeast   228 ---SHPK---------DEMCPKEYEASRTVIEFLILHASDIIPNT-EKANK 265
               :.|:         |.....|.:||...:.|:|.|...|.... ||.:|
  Fly  2069 SVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSK 2119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BAG7	NP_014777.3	RhoGAP_fSAC7_BAG7	47..257	CDD:239861	55/232 (24%)
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937
		RhoGAP_DLC1	1893..2116	CDD:239840	58/241 (24%)
		SRPBCC	2148..2343	CDD:301327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46587
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3060
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030