DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LMO4 and lmo4b

DIOPT Version :9

Sequence 1:	NP_001356420.1	Gene:	LMO4 / 8543	HGNCID:	6644	Length:	165	Species:	Homo sapiens
Sequence 2:	NP_997854.2	Gene:	lmo4b / 324849	ZFINID:	ZDB-GENE-030131-3570	Length:	165	Species:	Danio rerio

Alignment Length:	165	Identity:	159/165 - (96%)
Similarity:	163/165 - (98%)	Gaps:	0/165 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCY 65
            |||||.|:|||||.||||||||||||||||||||||||||||||||||||||||||||:||||||
Zfish     1 MVNPGGSAQPPPVGAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGEIGTSCY 65

Human    66 TKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHY 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    66 TKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHY 130

Human   131 INGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC 165
            ||||||||||||||||||||:|||:||||||||||
Zfish   131 INGSLFCEHDRPTALINGHLSSLQTNPLLPDQKVC 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LMO4	NP_001356420.1	LIM1_LMO4	23..77	CDD:188772	52/53 (98%)
LMO4	NP_001356420.1	LIM2_LMO4	87..141	CDD:188773	53/53 (100%)
lmo4b	NP_997854.2	LIM1_LMO4	23..77	CDD:188772	52/53 (98%)
lmo4b	NP_997854.2	LIM2_LMO4	87..141	CDD:188773	53/53 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194341278
Domainoid	1	1.000	131	1.000	Domainoid score	I20573
eggNOG	1	0.900	-	-		E33208_3BFEA
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4927
Inparanoid	1	1.050	346	1.000	Inparanoid score	I8764
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48264
OrthoDB	1	1.010	-	-		D1307952at2759
OrthoFinder	1	1.000	-	-		FOG0000888
OrthoInspector	1	1.000	-	-		oto47135
orthoMCL	1	0.900	-	-		OOG6_109625
Panther	1	1.100	-	-	LDO	PTHR45787
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10620
SonicParanoid	1	1.000	-	-		X8994
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	17	17.300