DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SKI7 and eEF1alpha1

DIOPT Version :9

Sequence 1:	NP_014719.1	Gene:	SKI7 / 854243	SGDID:	S000005602	Length:	747	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001286321.1	Gene:	eEF1alpha1 / 36271	FlyBaseID:	FBgn0284245	Length:	463	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	91/458 - (19%)
Similarity:	176/458 - (38%)	Gaps:	133/458 - (29%)

- Green bases have known domain annotations that are detailed below.

Yeast   266 LNLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKV--ILDNTKTER 328
            :::..:.:|..::||||..|||:|....|...::.:.:|::..:   ...|||.  :||..|.||
  Fly     6 IHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEM---GKGSFKYAWVLDKLKAER 67

Yeast   329 ENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSIL--TFDPEVYVLVIDCNYDSW 391
            |.|.::...:.:.|.    ....:|:||.||     :::.:.:::  |...:..||::......:
  Fly    68 ERGITIDIALWKFET----AKYYVTIIDAPG-----HRDFIKNMITGTSQADCAVLIVAAGTGEF 123

Yeast   392 EKSLDGPNNQIYEILKVISYLNKNSACKKH-----------LIILLNKADLIS--WDKHRLEMIQ 443
            |..                 ::||...::|           ||:.:||.|...  :.:.|.|.|:
  Fly   124 EAG-----------------ISKNGQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIK 171

Yeast   444 SELNYVLKENFQWTDAEFQFIPCSGLLGSN-LNKTENITKSK-YKSEFDSINYVPEWYEGPTFFS 506
            .|::..:|: ..:..|...|:|.||..|.| |..:.|:...| :|.|....|     .:|.|...
  Fly   172 KEVSSYIKK-IGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWKVERKEGN-----ADGKTLID 230

Yeast   507 QLYLLV---EHNMNKIETTLEEPF----VGTI----LQSSVLQP----------------IAEIN 544
            .|..::   ......:...|::.:    :||:    :::.||:|                ..|::
  Fly   231 ALDAILPPARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMH 295

Yeast   545 YVSLKVLI---NSGY-IQSGQTIEIHTQY-------------EDFHYYGIVSRMKNSKQILETNT 592
            :.:|:..:   |.|: :::....|:...|             .||           :.|::..|.
  Fly   296 HEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADF-----------TAQVIVLNH 349

Yeast   593 KNNISVGLNP-----------DILEVLVKI-----HNTEDFTKKQFHIRKGDIIIHSRKTNTLSP 641
            ...|:.|..|           ...|:..|:     ..||:..|   .|:.||..|.:     |.|
  Fly   350 PGQIANGYTPVLDCHTAHIACKFAEIKEKVDRRSGKTTEENPK---FIKSGDAAIVN-----LVP 406

Yeast   642 NLP 644
            :.|
  Fly   407 SKP 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SKI7	NP_014719.1	TEF1	261..747	CDD:227581	91/458 (20%)
eEF1alpha1	NP_001286321.1	PTZ00141	1..457	CDD:185474	91/458 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910