Protein Alignment APOL1 and LOC101730357

DIOPT Version :10

• Sequence 1: NP_663318.1
• Gene: APOL1 / 8542
• HGNCID: 618
• Length: 414
• Species: Homo sapiens
• Sequence 2: XP_031758861.1
• Gene: LOC101730357 / 101730357
• XenbaseID: XB-GENE-29084499
• Length: 353
• Species: Xenopus tropicalis
• Alignment Length: 311
• Identity: 79/311 - (25%)
• Similarity: 134/311 - (43%)
• Gaps: 75/311 - (24%)

Human   167 LEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELG 231
            :::.|..|..:||.::||||.|||||:...:..|:.||..:||:.|.|.|.|.|:::...|..:.
 Frog     8 MKECISLLYHIADCIEKVHKDTTIANIAGSTAGIAGGITAIVGLALIPVTLGASVIVSAVGGAVA 72

Human   232 ITAALTGITSSTMD--YGKKWWTQAQ------AHDL-----VIKSLD-KLKEVREFLGENISNFL 282
            ....|||..||.:|  |.||..::|:      .:|:     .:.::| :|:.::...|||.|.:.
 Frog    73 AAGGLTGAGSSIVDFFYIKKQCSEAEKILKAFMNDVKCIKDYLSNIDIQLEAIKSLFGENTSEYS 137

Human   283 SLAGNTYQLTRGIGKD----------IRALRRARANLQSVPHASASRPRVTEPIS---------- 327
            .......:....:.::          ..||::. |:|.:....:|..|.:.|..:
 Frog   138 RFTNYLLKFYLPLKEESLLFISENEGFNALKQF-ADLFNFKTLTALVPSLIETAAQAGSSGAKAA 201

Human   328 ------AESGEQV-------------------------ERVNEPSILEMSRGVKLTDVAP---VS 358
                  |.||.||                         .::....::.:|...|...:|.   |:
 Frog   202 SSGAQVASSGAQVASRGAQVASRGAQAASRGAQIASSEAQIASSGVVVVSSAAKAAVIASGVFVA 266

Human   359 FFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELE------EKLNILNN 403
            ..||:|:|:||..|||||||||:..|..::.:|..||      |..|:..|
 Frog   267 LGLVIDIVFLVKNSKHLHEGAKTAQAAAIRSIASALEKDSKAFEGKNVQEN 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APOL1	NP_663318.1	ApoL	104..403	CDD:461657	78/309 (25%)
LOC101730357	XP_031758861.1	ApoL	<8..290	CDD:461657	72/282 (26%)