Protein Alignment SLC22A16 and CG16727

DIOPT Version :10

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_650818.1
• Gene: CG16727 / 42338
• FlyBaseID: FBgn0038719
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 130/566 - (22%)
• Similarity: 238/566 - (42%)
• Gaps: 70/566 - (12%)

Human     6 FEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWS 70
            |:.:.:..|:|||||.|:..:..:.||...:||.:...:..||.|.|              |:..
  Fly     3 FDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTPEHWC--------------SHDD 53

Human    71 LEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEY---TGSKKEFPCVDGYIYD 132
            |...||.                   ||.....|....:.:|..|.   ||...|..|.| :|::
  Fly    54 LMGLGAA-------------------ELRSIYSNVSHPSCTLLSEVINGTGVASEESCQD-WIFE 98

Human   133 QNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGR--RVVLWATSSSMFLF 195
            :.....:..|:...|||:.....:.|..|..|.::|:::||:.||.:||  .:::.|.|.:...|
  Fly    99 RENGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAALSGATGDF 163

Human   196 GIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHSFFAVGTLLVAL 259
            ..:....:.::.|  :||...:.......:.::.|.|::..|.||:. ::.|..|:..|.:....
  Fly   164 ITSFVHTLPWFAF--SRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYCFGLMTSPW 226

Human   260 TGYLVRTW----WLYQM-ILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWN--RA 317
            ....:..|    ||..: .|..:..|.::|     |:..|||::.:|:||...:..:||:|  :.
  Fly   227 IAMWIGNWRRYLWLASLPALGVLIYPLLIC-----ESAQWLLTKKKYDEAVACLKKVAKFNGRQV 286

Human   318 SSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVN 382
            ......|.:....:.....|....|......:|....:.:.|.|:.:.....:|.:...:.|...
  Fly   287 EDSVFDEFVKHYREKMNEESKLNKQMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEG 351

Human   383 LGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVI----------PQ 437
            ||.:.:....|...|.:||...:.:..:|:||:     .:.|.||..|.::..          |.
  Fly   352 LGSSPFKLFSLTSSVYLPAGFTILLLQNKIGRK-----GMACGALLVGAIITAVTGFLIAVLDPS 411

Human   438 KHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIW 502
            ::.:|..:...:|:|....::.....|.||:.||.||..||.:..:|...:|.||.:.:.|:..:
  Fly   412 ENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLAQYY 476

Human   503 IFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENES 548
            ..:|.:|:..:..|..:|.|.|||||.|:|..|..:..:. :.|||
  Fly   477 KPLPSIFISVLMFLGALLCLTLPETLHKKLPETLADGERF-AMNES 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	MFS_SLC22A16_CT2	118..525	CDD:340933	93/426 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		3/6 (50%)
CG16727	NP_650818.1	2A0119	11..509	CDD:273328	125/543 (23%)