Protein Alignment SLC22A16 and CG17751

DIOPT Version :9

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_650816.3
• Gene: CG17751 / 42336
• FlyBaseID: FBgn0038717
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 589
• Identity: 138/589 - (23%)
• Similarity: 236/589 - (40%)
• Gaps: 88/589 - (14%)

Human     7 EGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSL 71
            :.:.:..|:||.:|.:|..:..:.||...:||.:...:..||.|.|..|
  Fly     4 QSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRP---------------- 52

Human    72 EDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTW 136
                       :||                   :..:||.|........|||.|.......::.:
  Fly    53 -----------EDY-------------------QPNSTSLLSCSVMQFDKEFKCTSWDFERESNY 87

Human   137 KS-TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRR---VVLWATSSSMFLFGI 197
            :| |...:|  |||..:...:.|..|..|..|||:.|||.:||:||.   |:...|.:|...|
  Fly    88 ESITTELEW--VCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFF-- 148

Human   198 AAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHSFFAVGTLLVALTG 261
             .:|......|...||...:......|:.::.|.|::..:.||:. ::.|..|:.||.::.....
  Fly   149 -TSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIA 212

Human   262 YLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWN--RASSCKLSE 324
            ..|..|..|....|...:..:|....|.|:..|||::|::|:|:|.:..:||:|  :.......|
  Fly   213 IWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDE 277

Human   325 LLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGS----LGFYSFSLNSVNLGG 385
            .:. ..:..::||     ::..|..|.....|.|.....:|....|    :.|...|.|...:|.
  Fly   278 FIK-HYREKLNNS-----QNKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI 336

Human   386 NEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSAL---ACG--VVMVIPQKHYILGVV 445
            :.:......|...:||...:.:..:|:||:.:...|||..|:   |.|  |..:.|..:.:|...
  Fly   337 SPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGF 401

Human   446 TAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFV 510
            ...:|::....|:.....|.||:.||.|:...|.:..:|....:..:.:.:.|.:.:..:|.|.:
  Fly   402 MVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMI 466

Human   511 GTMALLSGVLTLKLPETLGKRLATTWEEA---AKLES-------ENESKSSKLLLTTNNSGLEKT 565
            ..:.|:...|.|.|||||.|.|....||.   ||.|.       ....|:.|     :.:.||.:
  Fly   467 SFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQK-----SATQLESS 526

Human   566 EAIT 569
            :.||
  Fly   527 DGIT 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	127/536 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		7/34 (21%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	127/535 (24%)
		MFS	109..481	CDD:119392	90/380 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850