Protein Alignment SLC22A16 and CG7333

DIOPT Version :9

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 141/571 - (24%)
• Similarity: 245/571 - (42%)
• Gaps: 79/571 - (13%)

Human     6 FEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSN-W 69
            |..:.|..|::||||.::..:..:.||...:||.:...:..||.|.|          ||...| .
  Fly     3 FSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWC----------FHADLNGL 57

Human    70 SLEDTGALLSSGQKDYVT--VQLQNGE-IWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIY 131
            |:|...::..:......|  :.:.||. :...:|..||...|..| |||
  Fly    58 SVEGIRSVYENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRES-GYE---------------- 105

Human   132 DQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGR-RVVLWATSSSMFLF 195
                   :..|:...|||:.....:.|..|..|.::|::.|||.||::|| ..:|.||     |.
  Fly   106 -------SITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMAT-----LC 158

Human   196 GIAAAFAVDY-YT---FMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHSFFAVGTL 255
            |....|...: :|   |..:||...:.......:.::.|.|::..||||:. ::.|..|:..|.:
  Fly   159 GATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLM 223

Human   256 LVALTGYLVRTW----WLYQM-ILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWN 315
            ........:..|    ||..: .|..:..||::|     |:..|||::.:|::|...:..:||:|
  Fly   224 TSPWAAIWIGNWRRYLWLASLPALGVLIYPFLIC-----ESAQWLLTKRKYDDAVICLKKVAKFN 283

Human   316 R--ASSCKLSELLSL----DLQGPVSNSPTEVQKHNLSYL--FYNWSITKRTLTVWLIWFTGSLG 372
            |  .......|.:..    :||....||      |..::|  |....:.:.|||:.:.....:|.
  Fly   284 RRHVEESVFDEFVKYYRERELQDYKLNS------HEDTFLAMFLTPRLRRFTLTLLVKSVIITLS 342

Human   373 FYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSAL---ACG--VV 432
            ....:.|...||.:.:.......:|.:||...:.:..:|:||:.:...:||...|   |.|  :.
  Fly   343 CDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIA 407

Human   433 MVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVD 497
            .:.|.::.:|..:...:|:|....::.....|.||:.||.||..||.:..::...:|.||.:.:.
  Fly   408 HLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIY 472

Human   498 LSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENES 548
            |:..:..:|.:|:..:......|.|.|||||.|:|..|..:..|. :.|||
  Fly   473 LAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKF-ALNES 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	134/548 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		3/6 (50%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	134/548 (24%)
		MFS	126..499	CDD:119392	93/388 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153547
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850