Protein Alignment SLC22A16 and CG14856

DIOPT Version :9

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 128/570 - (22%)
• Similarity: 222/570 - (38%)
• Gaps: 94/570 - (16%)

Human     6 FEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWS 70
            |:.|....|...|:|.:|..:..........||.|...:|..|.|.|          :|.
  Fly     5 FDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWC----------YHE----- 54

Human    71 LEDTGALLSSGQKDYVTVQLQNGEIWELS---------RCSRNKRENTSSLGYEYTGSKKEFPCV 126
                              ||:|....|::         .|:|....|..  |...|.|.:  ||.
  Fly    55 ------------------QLENRSYAEIAAIYAPFKRPSCTRLASINMD--GSNATASSE--PCN 97

Human   127 DG-YIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSS 190
            .. |.||.......|...|  |||..:.|.:.|.||..|.:.|::.||...||:||...:...:.
  Fly    98 RWIYHYDHGFISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANC 160

Human   191 SMFLFGIAAAFAVDYYTFMAARFF--LAMVASGYLVVGFVYVMEFIGMKSRTWASVHLH----SF 249
            ..||...|..||....||.|:||.  ||..|:.||:  |:.|:|::   |.|..||.|:    .|
  Fly   161 CGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLM--FILVLEYV---SPTMRSVGLNLTMCVF 220

Human   250 FAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCC---WVLPETPFWLLSEGRYEEAQKIVDIM 311
            :.:|.:..:..|..:.:|   :..:....:|.:|..   :::.|:..||::...::.|:..:..:
  Fly   221 YGLGMICASWQGVWLGSW---RSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRV 282

Human   312 AKWNR-----------ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITK---RTLTV 362
            ||:||           ...||..|          |.:.:::.....:.|..::.:.:   |.:.|
  Fly   283 AKFNRRDVSEADYELFRQHCKTKE----------SEARSQMSMQKQARLIDSFKLPRLRLRLIYV 337

Human   363 WLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSAL 427
            .:::...:|.:.:.|.|...|..:.::...|..:...|:..|........||:.....|:..:.|
  Fly   338 TVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGL 402

Human   428 ---ACGVVMVIPQKH-YILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLA 488
               ..|:::....:| ..:.|...::.:|.|....|.....:.||.||.|||..:....:.....
  Fly   403 MTATTGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAAL 467

Human   489 SILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEE 538
            |.::||.:.|.:.:.....:....:.|:|..:.|.|.||..|:|..|..|
  Fly   468 SFISPFILHLDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	124/557 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	124/557 (22%)
		MFS	129..503	CDD:119392	85/391 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850