Protein Alignment SLC22A16 and CG14855

DIOPT Version :10

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 136/586 - (23%)
• Similarity: 236/586 - (40%)
• Gaps: 129/586 - (22%)

Human     6 FEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWS 70
            ||.|....|:..|:|.||..:..:..:...:||.:...:...|.|.|          :|.
  Fly     3 FEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWC----------YHE----- 52

Human    71 LEDTGALLSSGQKDYVTVQLQNGEIWELSR---------CSRNKRENTSSLGYEYTGSKKEFPCV 126
                              ||:|....|:.:         |:|  .|.....|..:|.|::.  |
  Fly    53 ------------------QLENRSFAEIEKIYSQFEKPSCTR--LEKIDEDGQNHTLSRER--C- 94

Human   127 DGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSS 191
            :.:||..:....:..|:.|.|||..:.|.:.|.||..|.:.|::.||...||:||...|...:..
  Fly    95 NRWIYKYDFGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWC 159

Human   192 MFLFGIAAAFAVDYYTFMAARFF--LAMVASGYLVVGFVYVMEFIGMKSR-TWASVHLHSFFAVG 253
            .||...:..||....:|..:||.  ||..|:.||:  ::.::|::....| ...:..|.||:.:|
  Fly   160 GFLGDFSTIFAGSLTSFSISRFISGLAADANSYLM--YILILEYVSPSLRNVGLNTVLGSFYCLG 222

Human   254 TLLVALTGYLVRTWWL------YQMILSTVTVPFILCC---WVLPETPFWLLSEGRYEEAQKIVD 309
                     |:...||      :::.|:..:||.:|..   :::.|:..||::....:.|.:.::
  Fly   223 ---------LIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLE 278

Human   310 IMAKWNRAS-----------SCKL-----------SELLSLDLQGPVSNSPTEVQKHNLSYLF-- 350
            .:||.||..           .|:.           ::||.: |:.|...|..    ..|..:|
  Fly   279 RVAKINRRQVADKDFKDFRIYCEQHYRKDKNQEEHAKLLDM-LKTPRMRSTA----FKLLLIFII 338

Human   351 ----YNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDK 411
                || :|.:.      :...|...|..||||::.|..:.||.    |:::           |:
  Fly   339 IVPCYN-TIARN------VEGLGISPFIMFSLNALTLPPSGYLQ----GLLQ-----------DR 381

Human   412 VGRR-TVLAYSLFCSALACGVVMVIPQ---KHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTI 472
            :||: |.:.:.......|....:||.|   ::.:|.|...|..:|.:..|.|....::.||.||.
  Fly   382 MGRKATAVGWMAITGIFAVAAGLVISQGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTS 446

Human   473 VRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWE 537
            ||...|....:....||.|:|:.:.|.:.:...|.:.:|.:.|....:.|.||||..|:|..:..
  Fly   447 VRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLA 511

Human   538 E 538
            |
  Fly   512 E 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	MFS_SLC22A16_CT2	118..525	CDD:340933	106/450 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	131/571 (23%)