Protein Alignment SLC22A16 and Balat

DIOPT Version :9

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 604
• Identity: 169/604 - (27%)
• Similarity: 277/604 - (45%)
• Gaps: 70/604 - (11%)

Human     6 FEGIYDHVGHFGRFQRVLYFICAF---QNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHS 67
            |:.:...||.||.:|:|:  ||:.   ..:.|..|..:.:|:..||.|.||.|.
  Fly     3 FDEVLREVGSFGLYQKVI--ICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPE----------- 54

Human    68 NWSLEDTGALLSSGQKDYVTV-------QLQNGEIWELSRCSRNKRENTSSLGYE---------- 115
                      |....:|||.:       :.:||...|.|..|||..:....|.|.
  Fly    55 ----------LEPWTQDYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQA 109

Human   116 ------YTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGY 174
                  ...:.:..||..|:.||::.:.||.|.:|||||||.:|..|...:|..|.|||:..|||
  Fly   110 EDLLKLQPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGY 174

Human   175 FSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSR 239
            ..|..|||...:|......:...|:|||.:|||::..||.:.:.....|...:|..:|.:|.:.|
  Fly   175 LVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERR 239

Human   240 TWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA 304
            .:.::..:..:::|.:::|...|:||.|....:.:|...:....|.:||||:|.||::.|:...|
  Fly   240 VFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRA 304

Human   305 QKIVDIMA-----KWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWL 364
            .||:.:||     :.||....:|...|.:.......:|.|  ..:.:..||...::.::||.:.|
  Fly   305 IKILKVMARVNGVRVNRDFVERLQRKLVITRAAETKSSMT--THYGILDLFRGPNMRRKTLIITL 367

Human   365 IWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALAC 429
            |||..:..:...|..:..|||:|..|.||.|.||:|.|..:...:...|||.:|..|:....:||
  Fly   368 IWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVAC 432

Human   430 GVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 494
            ....:.|.    :.::...|||..|.::|.::.|..:|||||:||.|.:...|::..:..|:.|.
  Fly   433 VATFLYPD----ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPM 493

Human   495 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLE--------SENESKSS 551
            ...:....:.:|.:.:|.:.:|.|..:|.||||..:.|..|.||...:.        .|:|.|.:
  Fly   494 INHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEAVPLSFLLCCCVESERKPN 558

Human   552 KLLLTTNNSGLEKTEAITP 570
            .:..:.....|  .||.||
  Fly   559 NIRASPKKRIL--PEAGTP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	156/551 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		8/36 (22%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	120/401 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880