Protein Alignment KAE1 and Tcs4

DIOPT Version :10

• Sequence 1: NP_012964.2
• Gene: KAE1 / 853910
• SGDID: S000001746
• Length: 386
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_608347.1
• Gene: Tcs4 / 32982
• FlyBaseID: FBgn0031060
• Length: 409
• Species: Drosophila melanogaster
• Alignment Length: 376
• Identity: 88/376 - (23%)
• Similarity: 144/376 - (38%)
• Gaps: 82/376 - (21%)

Yeast    19 LGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDT---YVTPPGEGFLPRDTARHHR 80
            ||:|.|.:..|:.||               |....:::|:.::   :.|..| |.:|......||
  Fly    28 LGIETSCDDTGIAIV---------------DTTGRVIANVLESQQEFHTRYG-GIIPPRAQDLHR 76

Yeast    81 NWCIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGH 145
            .......::.:..|.:|...|  ..|..|..||:...|...|..||..:.....||:.|:|...|
  Fly    77 ARIESAYQRCMEAAQLKPDQL--TAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAH 139

Yeast   146 IEMGREITKAQNP-------VVLYVSGGNTQ-VIAYSEKRYRIFGETLDIAIGNCLDRFARTLKI 202
            ....|    .::|       :.|..|||:.| |:|....|..:.|:|||.|.|...|:..|.|::
  Fly   140 ALQAR----MEHPEQIGYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRL 200

Yeast   203 PNEPSPGYNIEQLAKKAPHKENLV------ELPYTV---KGMDLSMSGILASIDLLAKDLFKGNK 258
              ...|.|.:....:...|...|.      |.|..:   :..:.|.:||            |.|.
  Fly   201 --HILPEYRLWNGGRAIEHAAQLASDPLAYEFPLPLAQQRNCNFSFAGI------------KNNS 251

Yeast   259 KNKI----LFDKTTGEQKVT-VEDLCYSLQENLFAMLVEITERAMAHV---------NSNQVLIV 309
            ...|    ..::|..:..:: ..|.|..|..::...|:..|:||:.:.         ::...|::
  Fly   252 FRAIRARERAERTPPDGVISNYGDFCAGLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVM 316

Yeast   310 -GGVGCN----VRLQEMMAQM-CKDRANGQVHATDNRFCIDNGVMIAQAGL 354
             |||..|    ..::.:.||. |:.      .....|:|.|||||||..|:
  Fly   317 SGGVANNDAIYANIEHLAAQYGCRS------FRPSKRYCSDNGVMIAWHGV 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KAE1	NP_012964.2	ASKHA_NBD_OSGEP_like_euk	17..360	CDD:466982	88/376 (23%)
Tcs4	NP_608347.1	ASKHA_NBD_OSGEPL1_QRI7_euk	27..366	CDD:466984	88/376 (23%)