Protein Alignment TUL1 and Rnf145

DIOPT Version :9

• Sequence 1: NP_012890.1
• Gene: TUL1 / 853832
• SGDID: S000001517
• Length: 758
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_001350095.1
• Gene: Rnf145 / 74315
• MGIID: 1921565
• Length: 663
• Species: Mus musculus
• Alignment Length: 444
• Identity: 91/444 - (20%)
• Similarity: 153/444 - (34%)
• Gaps: 173/444 - (38%)

Yeast   400 LLFGIALFAAQIY-----------------LLLTQMHH-TNTPSMVNKISFYCFSMINLVDGSLA 446
            ::|.:.|||.|||                 |.||.:.. .:||          :|::.||    .
Mouse   232 MVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTP----------YSLLGLV----F 282

Yeast   447 TLYFVAASVVP--ELYLP---------------------LVISAFSCFILASIFEIRYLISIYAS 488
            |:.|||..|:.  :.||.                     |:::..:..|...:....:|:||...
Mouse   283 TVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILF 347

Yeast   489 QVNEQNVGIINLLRGNTGTYDENRPRPAFIPDEGSIGGSLYGRF--------------------- 532
            .|      :.::|:......|     |..:....|...||:..|
Mouse   348 IV------VASILQSMLEIAD-----PIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMIC 401

Yeast   533 ------FFMLIIFTFLILSSTSWPRQLRMVFEYILIFILNSYWIPQIFRNAVKGIPSRRERARSS 591
                  |::|||.:..||:|.   :.|..:|.|:| |::..:               |:|..
Mouse   402 QFFHMDFWLLIIISSSILTSL---QVLGTLFIYVL-FMVEEF---------------RKEPV--- 444

Yeast   592 IGGNRSQNKMPLLWSFVIGTTIIRSLPV---VYVFTYSSNVFRHHKDV-HFVVFL----SLWLLF 648
                  :|...::: :|.||..:....|   |..:..|..:|.....: ..::|:    ::||..
Mouse   445 ------ENMDDVIY-YVNGTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRA 502

Yeast   649 QI---SILYSQDVLGSRWFLPKHTIPDGYSYFKPLSNEYISEHGGGTAEHTVDCAICMSDVPIYI 710
            |:   |.|..:|.:.....||..|            .|.:.:|..       .||||..|:
Mouse   503 QLGWKSFLLRRDAVNKIKSLPVAT------------QEQLEKHND-------ICAICYQDM---- 544

Yeast   711 EEIPETHKVDQHSYMVTPCNHVFHTSCLENWMNYKLQCPVCR------SPLPPL 758
                       .|.::|||:|.||..||:.|:..:..||:|.      |.||.|
Mouse   545 -----------KSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGL 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUL1	NP_012890.1	COG5540	320..758	CDD:227827	90/442 (20%)
Rnf145	NP_001350095.1	TRC8_N	8..506	CDD:372682	61/327 (19%)
		YLYF motif. /evidence=ECO:0000269|PubMed:29374057	81..84
		HRD1	<520..627	CDD:227568	27/102 (26%)
		RING-H2_RNF145	533..575	CDD:319598	18/63 (29%)
		RING-H2 finger (C3H2C3-type)	537..574	CDD:319598	17/51 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	587..663		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7680
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030