DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TUL1 and Pex10

DIOPT Version :9

Sequence 1:	NP_012890.1	Gene:	TUL1 / 853832	SGDID:	S000001517	Length:	758	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001261265.1	Gene:	Pex10 / 38182	FlyBaseID:	FBgn0035233	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	227	Identity:	50/227 - (22%)
Similarity:	78/227 - (34%)	Gaps:	74/227 - (32%)

- Green bases have known domain annotations that are detailed below.

Yeast   579 KGIPSRRERARSSI----GGNRSQNKMPLLWSFVIGTTIIRS------LPVVYVFTYS-SNVFRH 632
            |.||||..:..:.:    |.:..|..|..|.::|.....||:      ..::.....| |.|...
  Fly    85 KQIPSRLLQLIAIVLEFGGDSLFQRLMQKLDTYVANNDEIRTEIKPQLKKIIQRLRQSPSYVKAL 149

Yeast   633 HKDVHFV----------------VFLSLWLLFQISILYSQDVLG-------------SRWFLPKH 668
            ||.:.::                |.:..||..:.| ||...:||             |.|
  Fly   150 HKSLFYLDASKYQLSKRTTGINYVLIRHWLQPEFS-LYGYKILGVITFLQVSVSLAISGW----- 208

Yeast   669 TIPDGYSYFKPLSNEYISEHGGGTAE----------HTVDCAICMSDVPIYIEEIPETHKVDQHS 723
               |.:...|....|.|.:.|....:          :|..|.:|:.         |.:..
  Fly   209 ---DAWREHKRQQLESIKQAGKNFLQRSSSTKDVDPNTPQCILCLE---------PRSDS----- 256

Yeast   724 YMVTPCNHVFHTSCLENWMNYKLQCPVCRSPL 755
             .:|||.|:|..|||..|:..:.:||:||..|
  Fly   257 -SLTPCGHIFCWSCLLEWLEERDECPLCRESL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TUL1	NP_012890.1	COG5540	320..758	CDD:227827	50/227 (22%)
Pex10	NP_001261265.1	Pex2_Pex12	20..>173	CDD:282595	17/87 (20%)
Pex10	NP_001261265.1	zf-RING_2	244..284	CDD:290367	14/54 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910