DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TUL1 and rnf43

DIOPT Version :9

Sequence 1:	NP_012890.1	Gene:	TUL1 / 853832	SGDID:	S000001517	Length:	758	Species:	Saccharomyces cerevisiae
Sequence 2:	XP_002935238.2	Gene:	rnf43 / 100491274	XenbaseID:	XB-GENE-952685	Length:	689	Species:	Xenopus tropicalis

Alignment Length:	153	Identity:	31/153 - (20%)
Similarity:	52/153 - (33%)	Gaps:	50/153 - (32%)

- Green bases have known domain annotations that are detailed below.

Yeast   632 HHKDVHFVVFLSLWLLFQIS------ILYS-----------QDVLGSRWFLPKHTIPDGYSYFKP 679
            ||         .:|:|..::      :||:           ||.:..:..|....:.......:.
Frog   190 HH---------DIWILLTVAGTVMFFVLYAVARLLCRQPPPQDSIQQQTLLAISRLGTRRYQQRM 245

Yeast   680 LSNEYISEHGG-----GTAEHTVDCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLE 739
            |.::..|  ||     .|:.....||||:.:.            .|.....:.||.|.:|..|::
Frog   246 LKDQRAS--GGWVETASTSSSVPVCAICLEEF------------TDGQELRILPCCHEYHLGCVD 296

Yeast   740 NWMNYKLQCPVCR-----SPLPP 757
            .|:.....||:|.     |..||
Frog   297 PWLRQNHTCPLCMYDILDSGTPP 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TUL1	NP_012890.1	COG5540	320..758	CDD:227827	31/153 (20%)
rnf43	XP_002935238.2	ZNRF_3_ecto	80..182	CDD:375639
		HRD1	<244..366	CDD:227568	22/90 (24%)
		RING-H2_RNF43_like	267..311	CDD:319580	14/55 (25%)
		RING-H2 finger (C3H2C3-type)	268..308	CDD:319580	13/51 (25%)
		DUF4573	523..643	CDD:373595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910