Protein Alignment STE6 and CG1824

DIOPT Version :10

• Sequence 1: NP_012713.1
• Gene: STE6 / 853671
• SGDID: S000001692
• Length: 1290
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_572810.1
• Gene: CG1824 / 32208
• FlyBaseID: FBgn0030403
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 644
• Identity: 175/644 - (27%)
• Similarity: 302/644 - (46%)
• Gaps: 72/644 - (11%)

Yeast   672 VKVEEENIGYALKQQ---KNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPV 733
            ::.|||....|.:|.   |...:...|.|..:|..:...: .:.|..|.|..||..|:    |.:
  Fly   102 IRKEEEEEDTASEQHFDWKRLWTYLEPHLWELIGAVCAAL-IVAYINIRIPNLLGDLV----NTL 161

Yeast   734 FSYTFSFLLEGIVPS--TDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLR 796
            ..|..:::::.|..|  .|....:|:.|:.:.|        ...|.|...:||....|.....:|
  Fly   162 ARYANTYVMDPINNSFVKDVSKPASNLLSLYML--------QSGFTFMYIYLLSRVGEQMAAKMR 218

Yeast   797 NEVMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIWALVSG 861
            .::..::..:::.:|  :.|:..|:...:..|::|.::...:|:|....    |...||...:|.
  Fly   219 QDLFTQIVVQDIAFF--DENRTGELVNRLTADVQDFKTSFKQFVSQGLR----SAAQLIGGSISL 277

Yeast   862 WKLS----LVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENC---LYQIVTNIKTIKCLQA 919
            :.:|    .:.::..|.:::|....|   :|..:..|:|.||.|..   ..:.::||:|::....
  Fly   278 FMISPHMAAIALASVPCVVMFMTYLG---KKLRSLSKSSQAQAERATGVCEEALSNIRTVRSSAC 339

Yeast   920 EFHFQLTYHDLKIKMQQI--ASKRAIATGFGIS----MTNMIVMCIQAIIYYYGLKLVMIHEYTS 978
            |      |.::::...:.  |::.|...|:||:    :||..:..:.....:.|..|:      |
  Fly   340 E------YREMQLFEAETNEAARLAQKLGYGIAIFQGLTNFFLNTLVLSTLFMGGHLM------S 392

Yeast   979 KEMFTTFTLLLFTIMS---CTSLVS---QIPDISRGQRAASWIYRILDEKHNTLEVENNNARTVG 1037
            .|..:...|:.|.:.|   ..||..   .:..:.||..|.|.::..|     :|:.:....|...
  Fly   393 TESLSPGALMAFLVASQGVQRSLAQGSILLGTMIRGMSAGSRVFEFL-----SLQPQVELLRGYI 452

Yeast  1038 IAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGESGTGKSTLVLLLTK 1102
            |.....||:     :..:|::||||..|...|.|:.:..:..|||:.::|.||:||||:..|:.:
  Fly   453 IPQERLHGE-----IRFENVSFAYPMQPDHLVLKDFSLTLRPGQTVALVGASGSGKSTIASLVER 512

Yeast  1103 LYNCEVGKIKIDGTDVNDWNLTSLRKEI-SVVEQKPLLFNGTIRDNLTYGLQDEILEIEMYDALK 1166
            .|....|.||:||..::|.:...||..: ..:||:|:||..:|.:|:.||..| ..|.::|.|.:
  Fly   513 FYEPSAGNIKLDGYKLSDISPYWLRSNVLGFIEQQPVLFGTSILENIRYGKPD-AGEEDVYAAAR 576

Yeast  1167 YVGIHDFVISSPQGLDTRIDT--TLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIIN 1229
            ....||||.:.|.|..|.:..  |.|||||.||:.||||||:..:||||||.|||||:.|.:.:.
  Fly   577 LSQSHDFVTALPDGYATHVGERGTQLSGGQRQRIAIARALLKNPRILILDEATSALDATSEAEVQ 641

Yeast  1230 EIVKKGPPALLTMVITHSEQMMRSCNSIAVLKDGKVVERGNFDTLYNNRGELFQIVSNQ 1288
            :.:........|:||.|....:|:.:.|.||..|:|||.|..|.|...||..|::|..|
  Fly   642 KALDTVVQNRTTLVIAHRLSTIRNADLIVVLDQGRVVETGKHDELMGKRGLYFELVRQQ 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STE6	NP_012713.1	MdlB	1..592	CDD:440747
		MdlB	702..1290	CDD:440747	166/611 (27%)
CG1824	NP_572810.1	MdlB	119..702	CDD:440747	170/627 (27%)