Protein Alignment STE6 and CG3156

DIOPT Version :10

• Sequence 1: NP_012713.1
• Gene: STE6 / 853671
• SGDID: S000001692
• Length: 1290
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 169/606 - (27%)
• Similarity: 292/606 - (48%)
• Gaps: 74/606 - (12%)

Yeast    21 RNDY-RLLMI--------------MIIGTVATGLVPAITSILTGRVFDLLSVFVANGSHQGLYSQ 70
            |:.| |||.:              :::.:..|..||    :..|:|.|:  ||..:|......::
  Fly   106 RSQYGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVP----LFLGKVIDV--VFNKSGMDSAAMAK 164

Yeast    71 LVQRSM---AVMALGAASVPVMWLSLTSWMHIGERQGFRI----RSQILEAYLEEKPMEWYDNNE 128
            |.:.|:   .:..||.       .:..:.:|:......||    ||::..:.|.:: :.|:|..
  Fly   165 LGEYSVLLFGIFVLGG-------FANFARVHLFGNAALRIVRSLRSRLYRSMLMQE-VGWFDTK- 220

Yeast   129 KLLGDFTQINRCVEELRSSSAEASAITFQNLVAICAL---LGTSFYYSWSLTLIILCSSPIITFF 190
               |....|||...:........|......|.::..:   .|...|.|..|..:.....|.:...
  Fly   221 ---GTGELINRLSNDTLMVGTSLSQNVSDGLRSVAMIGVGTGMMIYTSPQLAAVSALVVPAMAGM 282

Yeast   191 AVVFSRMIHVYSEKENSETSKAAQLLTWSMNAAQLVRLYCTQRLERKKF-----KEIILNCNTFF 250
            |:|:.|.:...::.|..:.::..:.........:.|:.:|.::.|...|     :.:.:......
  Fly   283 AIVYGRYVRRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETR 347

Yeast   251 IKSCFFVAANAGILRFLTLTMFVQGFWFGSAMIKKGKLNINDVITCF-----HSCIMLGSTLNNT 310
            .::.||     |:..|....:.:...::|..::.:..|.|. .:|.|     :..|.:.. |:|.
  Fly   348 ARAIFF-----GLTGFCGNFIIISVLYYGGTLVLQDSLTIG-ALTAFMLYAGYVAISMNG-LSNF 405

Yeast   311 LHQIVVLQKGGVAMEKIMTLLKDGSKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVL 375
            ..|   |.||..|.|:|..:| |.....|::|.|.   ||:....::.|.||.|::|:||..|||
  Fly   406 YSQ---LNKGIGASERIWEIL-DRECSIPIDKGVV---PLEKPVGEVGFQNVFFTFPTRPESAVL 463

Yeast   376 KNVSLNFSAGQFTFIVGKSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQ 440
            .:.|||...|..|.:||:|||||:|::.|:||.||...|::.::|.:::|::.:.|..||..|.|
  Fly   464 TDFSLNLMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQ 528

Yeast   441 RCTLFNDTLRKNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVT 505
            ...||:.::|:|||.|:..   ....|....:.:|:|    |.:.:|...|||||:||:|..|:.
  Fly   529 EPVLFSCSIRENILYGANP---GETPSPERLQQVIED----ANVSQFTDQLPDGLDTLVGQRGMM 586

Yeast   506 LSGGQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQIESD 570
            |||||:||||||||.|::..||.||||.||||.|..||:..|:.:..:|:|.:.:.|.||.|.:.
  Fly   587 LSGGQKQRVAIARALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNA 651

Yeast   571 DYLYLMKEGEVVESGTQSELL 591
            |.:.::.:|::||.|:.:||:
  Fly   652 DQIAVLSDGKIVEQGSYNELM 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STE6	NP_012713.1	MdlB	1..592	CDD:440747	169/606 (28%)
		MdlB	702..1290	CDD:440747
CG3156	NP_569844.2	MdlB	103..687	CDD:440747	169/606 (28%)