DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GCN5 and fs(1)h

DIOPT Version :9

Sequence 1:	NP_011768.1	Gene:	GCN5 / 853167	SGDID:	S000003484	Length:	439	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001259321.1	Gene:	fs(1)h / 31722	FlyBaseID:	FBgn0004656	Length:	2046	Species:	Drosophila melanogaster

Alignment Length:	136	Identity:	45/136 - (33%)
Similarity:	75/136 - (55%)	Gaps:	10/136 - (7%)

- Green bases have known domain annotations that are detailed below.

Yeast   302 PIDPMTIPGLKEAGWTPEMDALAQRPKRGPHDA--AIQNILTELQNHAAAWPFLQPVN--KEEVP 362
            |::|  :.|:.:    |.:...|:||.|..:..  .|:.::..:..|..:|||.|||:  |..:|
  Fly    13 PVEP--VNGIVQ----PPVIPPAERPGRNTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLP 71

Yeast   363 DYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNK 427
            ||:..||:|||:.|::.:||:|.|...::.|.|...:||||.:||.........|..|||.|..|
  Fly    72 DYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQK 136

Yeast   428 VKEIPE 433
            ::.:|:
  Fly   137 IESMPK 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GCN5	NP_011768.1	COG5076	77..439	CDD:227408	45/136 (33%)
fs(1)h	NP_001259321.1	Bromo_Brdt_I_like	34..140	CDD:99929	37/105 (35%)
		COG5076	387..>593	CDD:227408
		Bromo_Brdt_II_like	481..581	CDD:99930
		BET	951..1015	CDD:293640
		BRD4_CDT	<2026..2046	CDD:293710
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900