Protein Alignment CYP4F2 and Cyp4d20

DIOPT Version :9

• Sequence 1: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 152/469 - (32%)
• Similarity: 239/469 - (50%)
• Gaps: 64/469 - (13%)

Human    84 YPQGFKVW-MGPISPLLSLCHPDIIR--SVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWS 145
            |.:.|:.| :|.     ||.:...::  ..|.:|..:..|.: .|.:|.|:|.||||:|.|.||.
  Fly    67 YGKTFRFWILGE-----SLIYTKDLQYFETILSSTTLLEKGQ-LYEYLRPFLNDGLLVSTGRKWH 125

Human   146 RHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSF 210
            ..|::.|.||||.:|:.|::|.:...::|....:.:| :|...:||.:::||..||.:.:.....
  Fly   126 ARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVA-DGKTAVDMLKYVSLAALDVITEAAMGV 189

Human   211 DSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQ-RFRRA-------------- 259
            ..:.|..|. .||.|   |.::|               |:.||.. ||.|.
  Fly   190 QVNAQNDPDFPYIKA---LKSVV---------------YIQPDRMFRFSRRYNWLFPLAAPLLHR 236

Human   260 -----CRLVHDFTDAVIQERRRTL----------PSQGVDDFLQAKAKSKTLDFIDVLLLSKDED 309
                 .|::|||||.||.|||.|:          |....|..:.:|::...||    :||....:
  Fly   237 QLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLD----ILLQSSIN 297

Human   310 GKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
            .:.|||.|||.|.|||||||.|||:||:|..||.:|:|||.|:|..:|:|.:|.......:....
  Fly   298 NQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQ 362

Human   375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEV 439
            |..|.:|...:||::||:||||.|.||..:::.:.| :.||......:.::..|.:...:|||..
  Fly   363 LQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDPLS 426

Human   440 YDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPEL 504
            :.|.||..:..:..:..|::||||||:|||||.||:.||||:::..|..:.:||...|.:.....
  Fly   427 FRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPMLNF 491

Human   505 VLRAEGGLWLRVEP 518
            :||:..|:.:.:.|
  Fly   492 ILRSASGINVGLRP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F2	NP_001073.3	DUF4175	4..>57	CDD:372724
		p450	52..515	CDD:365848	151/464 (33%)
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	148/455 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154781
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750