Protein Alignment CYP4F2 and Cyp318a1

DIOPT Version :9

• Sequence 1: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 559
• Identity: 127/559 - (22%)
• Similarity: 221/559 - (39%)
• Gaps: 143/559 - (25%)

Human     9 LGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVNPTEEG 73
            :.||...|             |||.:|||...   .|.||           .|...|.....::.
  Fly     5 IALWACGA-------------LLAVLLAWQQR---KCWRL-----------IWQLNGWRGVIQQP 42

Human    74 MRVLTQLVATYPQG-------FKV-WMGPIS------PLLSLCHPDIIRSVINASAAIAPKDKFF 124
            :..|...:..:|..       ::| :..|::      .||.:..|..:..|:||...:   ||
  Fly    43 VLWLLLCINLHPNSILEKVSQYRVHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECL---DK-- 102

Human   125 YSFLEP--WLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL------L 181
             :||:.  ::..|||.:.|.||...|:.|.|||..||:..:..:||...|.|..::|.      .
  Fly   103 -TFLQDGFFVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQ 166

Human   182 ASEGSACLDMFE----HISLMTLDSLQKCVFSFDSHCQEKPSEYIA----AILELSAL-VSKRHH 237
            |.:.:|..|:..    .:|.:|       :....::..:....:||    .:||:||: |.|...
  Fly   167 AVKFTAAEDLLSRAVLEVSCLT-------IMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWL 224

Human   238 EI-LLHIDFLYYLTPD-GQRFRRACRLVHDFTDAVIQERRRTL--------------PSQG---- 282
            :| |||    ..|.|: .:..::..:|:.||...:::.:.|..              .|.|
  Fly   225 QIRLLH----RLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRR 285

Human   283 --VDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLA 345
              ::...|..|..                  :::.|:|..||.:.:....:|.::.:...|..||
  Fly   286 IFIEQIFQLAANG------------------EMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLA 332

Human   346 KHP-EYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP 409
            .:. :.|.|...|::.|:.|  ..::..:.|..|.:|...:.|||||...||:..|||::|..|.
  Fly   333 TNKGDCQRRLLAEIRALVPD--VGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLA 395

Human   410 DGR----VIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF---DPENIKE-------------- 452
             ||    ::|:..|.::..|....:...| .:...:||.||   :.|.:.:
  Fly   396 -GRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQR 459

Human   453 --RSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489
              |...:|:|||.|.|:|||:.:.:..|||.|...:..|
  Fly   460 DRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F2	NP_001073.3	DUF4175	4..>57	CDD:372724	12/47 (26%)
		p450	52..515	CDD:365848	115/516 (22%)
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	113/495 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820