Protein Alignment LSG1 and Ns2

DIOPT Version :10

• Sequence 1: NP_011416.3
• Gene: LSG1 / 852779
• SGDID: S000003067
• Length: 640
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_611232.1
• Gene: Ns2 / 36989
• FlyBaseID: FBgn0034243
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 710
• Identity: 165/710 - (23%)
• Similarity: 276/710 - (38%)
• Gaps: 205/710 - (28%)

Yeast    13 PKGPKP-----THRKNK---NKLELGRAIKYARQKENAI-------EYLPDGEMRFT--TDKHEA 60
            |:.||.     .|.:.|   .:|::.|..|..|.:...|       ..||.|.|...  |.|
  Fly    25 PERPKSGLKGVAHPRTKGTIKRLQMYRNFKAKRDRTGKILTPAPFQGRLPAGTMARVEPTPK--- 86

Yeast    61 NWVKLRSVTQESALDEFLSTAALADKD----------------FTADRHSNVKIIRMDSGNDSAT 109
             |.....|..::||.:|......|.||                ..|.::..|.::..:|
  Fly    87 -WFSNSRVISQTALQKFQDEIGKAVKDPYQVIMKPSQLPVTLLNEAAKYKRVHLLDTES------ 144

Yeast   110 SQGFSMT---NEQRGNLNAKQRAL----------------AKDLIVPRRPEWNEGMSKFQLDRQE 155
               |..|   .:||..::.|.|.|                ||||.:.|.            |..|
  Fly   145 ---FDSTFGPKKQRKRVSLKVRDLEDLSKAADDQADKYDSAKDLDLIRE------------DTGE 194

Yeast   156 KEAFLEWRRKLAHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSVDLER 220
            |:|..:|               :....::..:|.:|.:||:.||:::|::|||:|:..||..:|.
  Fly   195 KKAVRDW---------------VFGAGQSKRIWNELHKVVDASDVLLQVLDARDPMGTRSKYIEE 244

Yeast   221 YVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQKEMGEDYREQ 285
            ::::....|....::||.||:.......|.....::..:..|:::|        |...|
  Fly   245 FLRKEKPHKHLFFILNKVDLVPVWVTQRWVAILSAEYPTIAFHASL--------QHPFG------ 295

Yeast   286 DFEEADKEGFDADEKVMEKVKILSI-DQLEELFLSKAPNEPLLPPLPGQPPLINIGLVGYPNVGK 349
                              |..:::: .||.:|.|.|..              |::|.:|||||||
  Fly   296 ------------------KGALINLFRQLGKLHLDKKQ--------------ISVGFIGYPNVGK 328

Yeast   350 SSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVFPNFAYNKGELVCNGVLPIDQL 414
            ||.||:|...|...|:...|:||.:|.|.|...:.|.||||:|:|. |....|.|..||:.::.:
  Fly   329 SSVINALRSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPT-AETDTEKVLKGVVRVELV 392

Yeast   415 ---RDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRDEGGNGDIPTAQELLVAYARARGYMTQGYG 476
               .||:..   :.:|:...||...|.|        |..|    |:...|...|:..|.:.:| |
  Fly   393 TNPEDYVDS---LLKRVRPEYISKNYKI--------EHWN----TSTHFLEQLAQKTGKLLKG-G 441

Yeast   477 SADEPRASRYILKDYVNGKLLYVNPP-----PHLEDDTPYTREE---CEEFNKD------LYVFD 527
            ..|....:|.:|.|:..|||.:..||     |..::.    :||   .|:.|:|      .:|.:
  Fly   442 EPDVTVTARMVLNDWQRGKLPFYVPPEGFAVPKSQEG----KEEEVVAEDPNEDAKSEAPTFVSE 502

Yeast   528 RLPDTRK-EQVQNAAKAK-GI-----DIVDLAR-DLNQLTFSAHTGGDTQKEAKSVTHGGKQAAL 584
            .:...|: :|:|:..|.: |:     |:.||.. ||..|        :.||..::..   |:|.:
  Fly   503 SVKKAREFKQIQDFRKIRVGLEYEQEDVKDLDHIDLELL--------EQQKAERAAK---KKARI 556

Yeast   585 YNAAEDLDR------DFFKMNNVEGRLSTPFHKVQNSSAGKRHNKKNKSKNAKSKVFSIE 638
            :|..|:.:.      :|:..:.....|....||...|   |:..:...:.:.|.:|..|:
  Fly   557 HNLGEEDEESSDGADEFYSEDEYNEDLQRVVHKKAKS---KKPQQLAITSSGKFRVAKIQ 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LSG1	NP_011416.3	HSR1_MMR1	187..394	CDD:206750	58/207 (28%)
		RbgA	199..496	CDD:440775	79/300 (26%)
Ns2	NP_611232.1	NGP1NT	49..179	CDD:462379	28/142 (20%)
		NGP_1	214..370	CDD:206751	55/201 (27%)
		PTZ00121	<474..657	CDD:173412	32/158 (20%)