DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAL31 and CG33282

DIOPT Version :9

Sequence 1:	NP_009857.1	Gene:	MAL31 / 852601	SGDID:	S000000502	Length:	614	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	92/450 - (20%)
Similarity:	174/450 - (38%)	Gaps:	78/450 - (17%)

- Green bases have known domain annotations that are detailed below.

Yeast   142 DYEIS---VSWQIGLCLCYMAGEIVGLQMTGPSVDYMGNRYTLIM---------ALFFLA---AF 191
            |:|::   :||         .|.::||       |.:....|:.|         .|:.:|   |.
  Fly    53 DFEVNLAQISW---------LGSMLGL-------DSLCGNLTIAMLIERAGRKFCLYLMAGPYAC 101

Yeast   192 IFILYFCKS-LGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWAFGQLFAAG 255
            |:||.:|.| :..:...:.|||...|....:...:.||:....:|..||:...|....|.|  ||
  Fly   102 IWILIYCASNVYYLYAARFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGIL--AG 164

Yeast   256 IMKNSQNKYANSELGYKLPFALQWIWPLPLAVGIFFAPESPWWLVKKGRIDQARRSLERTLSGKG 320
            .:.::...|      :.:|| |..|.|:...:.....||:..:|:||.::..|..|.....:.:.
  Fly   165 YILSTYLAY------HVVPF-LAIILPVAYFIANIMLPETAPYLLKKSQLAAAENSFRYYRNQRS 222

Yeast   321 PEKELLVSMELDKIKTTIEKEQ-KMSDEGTYWDCVKDGINRRRTRIACLCWIGQCSCGASLIGYS 384
            ...|....:..::::|.:..:| :.:...:|.|.......:.......|....|.|...|.|.|.
  Fly   223 AICEQTSKVNFEELRTAVLSQQTRNATPLSYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYM 287

Yeast   385 TYFYEKAGVSTDTAFTFSIIQYCLGIAATFISWWASKYCGRFDLY---AFGLAFQAIMFFIIGGL 446
            :..::.:|...|.. |.:||...:.|...:.|.......||..|.   ..|:....|.|
  Fly   288 SDIFKASGSVVDVN-TATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAF------ 345

Yeast   447 GC----------SDTHGAKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRT-----KTIIL 496
            ||          ||.:...:   .|::::.:..|:|:..:.|.::.|:...::|:     ..|.|
  Fly   346 GCFTYLAKIYDLSDFNWLPL---VLMIIICYVANIGLIGIFFLVLVELFPVKIRSLATSLSVIFL 407

Yeast   497 ARNAYNVIQVVVTVLIMYQLNSEKWNWGAKSGFFWGGFCLATLAWAVVDLPETAGRTFIE 556
            :...:..:::...:|..:.::...|        |.....|.|..:..:.|.||.|::.||
  Fly   408 SLLVFGTLKLFPLMLHYWGISFTMW--------FSAASALLTFFYFWLFLQETKGKSMIE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAL31	NP_009857.1	SP	74..557	CDD:273317	91/449 (20%)
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	86/437 (20%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	81/390 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830