DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment IKBKG and key

DIOPT Version :9

Sequence 1:NP_001093326.2 Gene:IKBKG / 8517 HGNCID:5961 Length:487 Species:Homo sapiens
Sequence 2:NP_001246503.1 Gene:key / 37967 FlyBaseID:FBgn0041205 Length:389 Species:Drosophila melanogaster


Alignment Length:398 Identity:93/398 - (23%)
Similarity:141/398 - (35%) Gaps:130/398 - (32%)


- Green bases have known domain annotations that are detailed below.


Human   109 LPSEQGAPE---TLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARK 170
            |.|.||:.|   .||..:.|...|:..:.:.||.:                              
  Fly   101 LCSLQGSAEEVVKLQNMMTEYLALKSTLDKVNQTM------------------------------ 135

Human   171 LVERLGLEKLDLKRQKEQALRE---VEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAAT 232
                |....|..:.::|.|.||   .||:|.||           ||:..|..|.||.:..||...
  Fly   136 ----LNYHNLTQQWRQEAADREHQYKEHVKECQ-----------AQIAILRVENQELKRDLETKI 185

Human   233 KECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQ 297
            ::.:.:........::.|:..||:::|.....|::|:|:....|.|.......::.|:|..|..|
  Fly   186 EQIEGVHTIRLKEQDELRKSVSEKQSLIDNMRVEIDKLKQLNHSFEFVPEYATESKSQELIKKMQ 250

Human   298 LQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIV 362
            |.:          |.:|:        |.:|                 |||||..           
  Fly   251 LDI----------NELKA--------RDIQ-----------------KQEVIKG----------- 269

Human   363 METVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKL--------KAS--CQE 417
                  |:.|.|||:.||:.||..|||.|.:|:.....|..|||...:|        |||  |..
  Fly   270 ------LQIQNDIYRRDFEMERADREKNAGEKDQYLMDLRSLQRRNQELIEALAESHKASKACST 328

Human   418 SARIEDMRKRHVEVSQAP---LPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQ 479
            ::.:...|. ::...|.|   |.|..|         |.|.|    .....||.|......:..||
  Fly   329 ASPLSSSRS-NLREEQRPVRILDPTGA---------SSRTS----DTTLRCPICSKSFNALSVLQ 379

Human   480 IHVMECIE 487
            .||.:|::
  Fly   380 SHVNDCLD 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IKBKGNP_001093326.2 NEMO 112..179 CDD:288434 10/69 (14%)
CC2-LZ 327..412 CDD:293124 25/92 (27%)
keyNP_001246503.1 DUF499 <168..>351 CDD:303008 56/235 (24%)
UBAN 230..313 CDD:197361 33/134 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D326045at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.