Protein Alignment MCD1 and vtd

DIOPT Version :9

• Sequence 1: NP_010281.1
• Gene: MCD1 / 851561
• SGDID: S000002161
• Length: 566
• Species: Saccharomyces cerevisiae
• Sequence 2: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 134/627 - (21%)
• Similarity: 232/627 - (37%)
• Gaps: 196/627 - (31%)

Yeast    14 LATNKGPLAQIWLASNM-SNIPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQG 77
            :...|||||:||||::. ..|.:..|.:|:|.:|.:.|.:         ....:.|||||.||.|
  Fly     7 ILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQ---------PKVKLALRTSGHLLLG 62

Yeast    78 IVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPG 142
            :||:||::|.:||.|..:...||.|.|:..         :..:...|:....:|:|..||
  Fly    63 VVRIYSRKAKYLLADCNEAFVKIKMAFRPG---------MVDLPEGHREANVNAITLPEV----- 113

Yeast   143 LEFLD-DTTIPVGLMAQENSMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGP 206
              |.| ||.:|     :.|.::.:.|.:.....:.|:..|    ||:...:||
  Fly   114 --FHDFDTALP-----ELNDIDIEAQFSINQSRADEITMR----EDYGSLSLS------------ 155

Yeast   207 ITSKSWEEGTRQSSRNFDTHENYIQDDDFPLDDAGTIGWDLGITE---------KNDQNNDDDDN 262
                                   :|||.|     |.||::....|         .||:..|:|
  Fly   156 -----------------------LQDDGF-----GDIGFEAETPEIIRCSIPSNINDKIFDND-- 190

Yeast   263 SVEQGRRLGESIMSEEPTDFGFDLDIEKEAPAGNI--DTITDAMTE------------SQPKQTG 313
                   :.|:|.|.:|    ..||...:.|...:  |...|:..:            |||.:..
  Fly   191 -------VLENIESLDP----HSLDAHADMPGSRLDGDGFGDSFGQPALFEDDLFGDPSQPVEQI 244

Yeast   314 TRRNSKLLNTKSIQID--EETENSESIASS--NTYKEERSNNLLTPQ-------PTNFTTKRLWS 367
            |:.::.:||......|  :...|..|.|:|  |:.::|:..|.|...       |.|
  Fly   245 TKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPMN-------- 301

Yeast   368 EIT----ESMSYLPDPILKNFLSYESL----KKRKIHNGREGSIEEPELNVSLNLTDDVISN--- 421
            |||    |...:...|:  :...|:.:    :|||:......:|...|:...|..|.|:::.
  Fly   302 EITLVQNEDEGFALAPL--DVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDL 364

Yeast   422 ---------------------------------AGTNDNSFNELT--DNMSDFVPIDAGLNEAPF 451
                                             ...|...|:..|  ::.|..||::....|. :
  Fly   365 APPTKRLMYWKETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALEF-Y 428

Yeast   452 PEEN-----IIDAKTRNEQT-TIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKS 510
            .:||     |.:.|.|..:. .:....:...|..|...  ::..::||   :..|.:..:.|...
  Fly   429 TKENENALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQS--LEAPEVLR---ANHKSLGVSTVSVE 488

Yeast   511 QANTEPENIT-KREASRGFFDILSLATEGCIGLSQTEAFGNI 551
            ..:.|.|:|: :.|.:  |||  ::.:...:.|::.|.|.:|
  Fly   489 IVSKEQESISCQNELT--FFD--NMRSPDLLSLNEMEQFSSI 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MCD1	NP_010281.1	Rad21_Rec8_N	17..108	CDD:398479	35/91 (38%)
		Rad21_Rec8	505..559	CDD:335912	12/48 (25%)
vtd	NP_001015132.1	Rad21_Rec8_N	1..106	CDD:282655	36/116 (31%)
		Rad21_Rec8	657..710	CDD:282654

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343725
Domainoid	1	1.000	62	1.000	Domainoid score	I2495
eggNOG	1	0.900	-	-		E1_KOG1213
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001363
OrthoInspector	1	1.000	-	-		oto99349
orthoMCL	1	0.900	-	-		OOG6_103388
Panther	1	1.100	-	-	LDO	PTHR12585
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1058
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.860