Protein Alignment NDST2 and Hs3st-B

DIOPT Version :10

• Sequence 1: NP_003626.1
• Gene: NDST2 / 8509
• HGNCID: 7681
• Length: 883
• Species: Homo sapiens
• Sequence 2: NP_573370.1
• Gene: Hs3st-B / 32918
• FlyBaseID: FBgn0031005
• Length: 384
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 78/267 - (29%)
• Similarity: 133/267 - (49%)
• Gaps: 29/267 - (10%)

Human   603 LPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNA 667
            ||..||:|.:|:||.|:..|:.|||.|.::      ..|:.||:. :|.:|:.||...  :|...
  Fly   131 LPDTLIIGVKKSGTRALLEFIRLHPDVRAA------GSEVHFFDR-HYQRGLRWYRHH--MPYTI 186

Human   668 STDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG------DPVALN 726
            ......||:.:||.::.||:|...:.|..|::.|:.:|..||.|.|....:..      :.:|..
  Fly   187 EGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFV 251

Human   727 YTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESI 791
            ...|.|:. ::..|:.:          |.|:.:|:|||.|:|..|||.:.|:.|..:||..:..:
  Fly   252 NGSYSVVD-TNWGPVKI----------GVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRV 305

Human   792 QKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKT--RCLGRSKGRRYPDMDTESRLFLTDFFRNH 854
            |.|||:...:. .:...|:..|||.|......::  .|||::|||.:|.:|..:...|.:|:|..
  Fly   306 QDFLGLKRVVT-EKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPF 369

Human   855 NLELSKL 861
            |.:..:|
  Fly   370 NNKFYQL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NDST2	NP_003626.1	Heparan sulfate N-deacetylase 2	41..597
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..81
		HSNSD	83..514	CDD:463450
		Heparan sulfate N-sulfotransferase 2	598..883		78/267 (29%)
		Sulfotransfer_1	603..852	CDD:425820	75/256 (29%)
Hs3st-B	NP_573370.1	Sulfotransfer_1	131..368	CDD:425820	75/257 (29%)