DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAL2 and CG33282

DIOPT Version :9

Sequence 1:	NP_013182.1	Gene:	GAL2 / 850770	SGDID:	S000004071	Length:	574	Species:	Saccharomyces cerevisiae
Sequence 2:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	109/500 - (21%)
Similarity:	197/500 - (39%)	Gaps:	115/500 - (23%)

- Green bases have known domain annotations that are detailed below.

Yeast    78 VAFG-GFMFGWDTGTISGFVVQT-----DFLRRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFGG 136
            :.|| |...||.:.|::  .:||     ||             .::..:...:.::..:....|.
  Fly    27 ITFGHGVGVGWLSPTLT--KIQTADSPLDF-------------EVNLAQISWLGSMLGLDSLCGN 76

Yeast   137 IILSKGGDMYGRKKGLSIVVSVY-IVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISE 200
            :.::...:..|||..|.::...| .:.|:|..|| |.:|.| ..|.:.|...|...::.|:.|||
  Fly    77 LTIAMLIERAGRKFCLYLMAGPYACIWILIYCAS-NVYYLY-AARFLCGFTGGAGYLVVPIFISE 139

Yeast   201 IAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPES 265
            :|..::||.|.|...|.:..||..||.       .|..:.:.|...|.....:....|..::||:
  Fly   140 VADSNIRGALTSMVMLSVDLGILAGYI-------LSTYLAYHVVPFLAIILPVAYFIANIMLPET 197

Yeast   266 PRYLCEVNKVEDAKRSI-----------AKSNKVSPED--PAVQAELDLIMAGIEAEKLAGNASW 317
            ..||.:.:::..|:.|.           .:::||:.|:  .||.:         :..:.|...|:
  Fly   198 APYLLKKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAVLS---------QQTRNATPLSY 253

Yeast   318 GELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVG-LDDSFETSIVIGVVNFASTF 381
            .:|  |.....:.....:.:.:..|.:|...|..|.:.|||:.| :.|....:|:||:|.....:
  Fly   254 KDL--TTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLVQIVGVY 316

Yeast   382 FSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCF----- 441
            .|...|:.:|.|..:|:                            |:.|.|...|.|.||
  Fly   317 TSTILVDIVGRRVLMLI----------------------------STMGVGIGCIAFGCFTYLAK 353

Yeast   442 ---------------YIFCYATTWAPVA--WVITAESFPLRVKSKCMALASASNWVWGFLIAFFT 489
                           .|.||......:.  :::..|.||::::|    ||::.:.::..|:.|.|
  Fly   354 IYDLSDFNWLPLVLMIIICYVANIGLIGIFFLVLVELFPVKIRS----LATSLSVIFLSLLVFGT 414

Yeast   490 PFITSAINFYYGYVF-----MGCLVAMFFYVFFFVPETKGLSLEE 529
            ..:...:..|:|..|     ....:..|||.:.|:.||||.|:.|
  Fly   415 LKLFPLMLHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSMIE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAL2	NP_013182.1	Sugar_tr	74..534	CDD:278511	108/499 (22%)
GAL2	NP_013182.1	MFS	75..518	CDD:119392	102/487 (21%)
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	102/487 (21%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	85/420 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342561
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.830