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Protein Alignment PARG and Parg

DIOPT Version :9

Sequence 1:	NP_003622.2	Gene:	PARG / 8505	HGNCID:	8605	Length:	976	Species:	Homo sapiens
Sequence 2:	NP_001245511.1	Gene:	Parg / 31329	FlyBaseID:	FBgn0023216	Length:	723	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	239/567 - (42%)
Similarity:	333/567 - (58%)	Gaps:	50/567 - (8%)

- Green bases have known domain annotations that are detailed below.

Human   417 LPKAEDRRKEQWETKHQRTERKIPKYVPPHL--SPDKKWLGTPIEEM--RRMPRCGIRLPLLRPS 477
            :.|:.|....:.||:.:          |.:|  |.|..|.|..:|.:  .|.|.....||.:...
  Fly     1 MSKSPDGGISEIETEEE----------PENLANSLDDSWRGVSMEAIHRNRQPFELENLPPVTAG 55

Human   478 ANHTVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTA 542
            ..|.|..::.:...  .|:|:.:..|  ||::||::||:.::.||.|:.:|..|...|||:|:.|
  Fly    56 NLHRVMYQLPIRET--PPRPYKSPGK--WDSEHVRLPCAPESKYPRENPDGSTTIDFRWEMIERA 116

Human   543 LLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNI 607
            ||......:.|:.||:.||..|..:|.|.||....|:.|:|:|.:..::.:||.::::||.||::
  Fly   117 LLQPIKTCEELQAAIISYNTTYRDQWHFRALHQLLDEELDESETRVFFEDLLPRIIRLALRLPDL 181

Human   608 CTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNA-KMKSEYSSYPDINFNRLFEGRSSR 671
            ...|:||||...|.|:::||:||:.||||||.|||||||. |.|||||::||||||||::.....
  Fly   182 IQSPVPLLKHHKNASLSLSQQQISCLLANAFLCTFPRRNTLKRKSEYSTFPDINFNRLYQSTGPA 246

Human   672 KPEKLKTLFCYFRRV--TEKK----PTGLVTFTRQS--LEDFPEWERCEKPL--TRLHVTYEGTI 726
            ..||||.:..|||||  ||:.    |||:|||.|:|  .|...:|.:...||  ..|||..||||
  Fly   247 VLEKLKCIMHYFRRVCPTERDASNVPTGVVTFVRRSGLPEHLIDWSQSAAPLGDVPLHVDAEGTI 311

Human   727 EENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSE 791
            |:.|.|:|||||||:::||||...|.|||||||:|.|||::.:||||.|...|.|::.|.|:||.
  Fly   312 EDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGAERYSN 376

Human   792 YTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCGFLR-- 854
            |||||.::.||.:.||.:.||...||.|.|||||||||.:...|:..:.|.|||||||.||:.
  Fly   377 YTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELNKAYIGFVHWM 441

Human   855 ----PGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYFTFGDSELMRDIYSMH 915
                ||        ||||||||||||||:.||||:|::..|...|.:.|:|||:.|...|.:.|.
  Fly   442 VTPPPG--------VATGNWGCGAFGGDSYLKALLQLMVCAQLGRPLAYYTFGNVEFRDDFHEMW 498

Human   916 IFLTERKLTVGDVYKLLLRYYNEECRNCSTPGP------DIKLYPFI 956
            :.......||..::. :||.|:...:..|:..|      ..|||.||
  Fly   499 LLFRNDGTTVQQLWS-ILRSYSRLIKEKSSKEPRENKASKKKLYDFI 544

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.